国际儿科学杂志
國際兒科學雜誌
국제인과학잡지
INTERNATIONAL JOURNAL OF PEDIATRICS
2014年
3期
295-297
,共3页
性发育障碍%环境内分泌干扰物%机制
性髮育障礙%環境內分泌榦擾物%機製
성발육장애%배경내분비간우물%궤제
Disorder of sexual development%Environmental endocrine disruptor%Mechanism
儿童性发育障碍是成因复杂、临床表现多样的一类疾病,近年来发病率逐渐上升,发病机制正被不断揭示.环境内分泌干扰物被认为可以干扰正常性别分化过程,导致性发育障碍的产生.该文主要综述环境内分泌干扰物干扰性别分化过程的机制,探讨环境内分泌干扰物和儿童性发育障碍发病之间的关系.
兒童性髮育障礙是成因複雜、臨床錶現多樣的一類疾病,近年來髮病率逐漸上升,髮病機製正被不斷揭示.環境內分泌榦擾物被認為可以榦擾正常性彆分化過程,導緻性髮育障礙的產生.該文主要綜述環境內分泌榦擾物榦擾性彆分化過程的機製,探討環境內分泌榦擾物和兒童性髮育障礙髮病之間的關繫.
인동성발육장애시성인복잡、림상표현다양적일류질병,근년래발병솔축점상승,발병궤제정피불단게시.배경내분비간우물피인위가이간우정상성별분화과정,도치성발육장애적산생.해문주요종술배경내분비간우물간우성별분화과정적궤제,탐토배경내분비간우물화인동성발육장애발병지간적관계.
Disorder of sexual development(DSD) refers to a group of diseases with various causes and phenotypes.It has attracted great worldwide as the incidence is rising and the life-long consequences accompanying.Environmental endocrine disruptors(EED) are thought to have an impact of the sex differentiation process and induce disorder of sexual development.This review summarizes the mechanism of DSD that associated with EED and focus on the relationship between DSD and EED.
