CAJ | 학술논문

目的探讨18F-FDG PET-CT在霍奇金淋巴瘤(HL)疗效评价中的临床价值.方法回顾性分析31例HL患者化疗后的18F-FDG PET-CT图像资料,最终结果经病理和临床随访证实,并与治疗后单纯CT结果进行对比分析,采用四格表x2进行差异的显著性检验.结果 ①31例患者共发现病灶145处,其中恶性94处、良性51处.18F-FDG PET-CT评价HL治疗效果的灵敏度、特异度、阳性预测值、阴性预测值及准确率分别为97.87％、94.12％、96.84％、96.00％和96.55％,均明显优于单纯CT检查(x2=9.83、13.49、11.50、11.69、22.58,P均＜0.05).②31例患者经PET-CT显像后,16例(51.61％)更改治疗方案.结论 18F-FDG PET-CT是HL疗效监测的有效手段.
목적 탐토18F-FDG PET-CT재곽기금림파류(HL)료효평개중적림상개치.방법 회고성분석31례HL환자화료후적18F-FDG PET-CT도상자료,최종결과경병리화림상수방증실,병여치료후단순CT결과진행대비분석,채용사격표x2진행차이적현저성검험.결과 ①31례환자공발현병조145처,기중악성94처、량성51처.18F-FDG PET-CT평개HL치료효과적령민도、특이도、양성예측치、음성예측치급준학솔분별위97.87％、94.12％、96.84％、96.00％화96.55％,균명현우우단순CT검사(x2=9.83、13.49、11.50、11.69、22.58,P균＜0.05).②31례환자경PET-CT현상후,16례(51.61％)경개치료방안.결론 18F-FDG PET-CT시HL료효감측적유효수단.
Objective To explore the clinical value of 18F-FDG PET-CT in the evaluation of efficacy of Hodgkin lymphoma (HL).Methods Thirty-one cases of post-treatment patients with HL were studied retrospectively.18F-FDG PET-CT images after chemotherapy were compared with CT post-therapy results.The final diagnosis was based on pathology or clinical follow-ups.Results ①A total of 94 malignant lesions and 51 benign lesions were found in 31 patients in the study.The sensitivity,specificity,positive predictive value,negative predictive value,and accuracy of 18F-FDG PET-CT in the evaluation of efficacy of HL were 97.87％,94.12％,96.84％,96.00％ and 96.55％ respectively,which were significantly superior to CT examination alone (x2=9.83,13.49,11.50,11.69,22.58,all P＜0.05).②According to the results of PET-CT,therapeutic schedules of 16 cases (51.61％)had been changed.Conclusion 18F-FDG PET-CT is an effective method in the evaluation of efficacy of HL.