CAJ | 학술논문

目的探讨18F-FDG PET/CT在多发癌诊断中的价值.方法回顾性分析5822例疑似肿瘤患者,均行18F-FDG PET/CT全身检查,经过活检或手术证实为多发癌患者32例.以病理结果作为金标准,以PET平均标准化摄取值(SUVmax)≥2.5且CT上有形态学改变者作为PET/CT判断恶性肿瘤的标准,计算PET/CT诊断多发癌的灵敏度和准确率.结果本组患者中多发癌的发生率为0.55％,其中,双发癌30例、三发癌2例,共66个原发灶.32例多发癌的66个原发灶的SUVmax的平均值为6.68±3.61.PET/CT诊断多发癌原发灶真阳性为58个,假阴性为8个.PET/CT诊断多发癌的灵敏度为87.9％,准确率为87.9％.结论 18F-FDG PET/CT全身检查诊断多发癌具有较大价值.
목적 탐토18F-FDG PET/CT재다발암진단중적개치.방법 회고성분석5822례의사종류환자,균행18F-FDG PET/CT전신검사,경과활검혹수술증실위다발암환자32례.이병리결과작위금표준,이PET평균표준화섭취치(SUVmax)≥2.5차CT상유형태학개변자작위PET/CT판단악성종류적표준,계산PET/CT진단다발암적령민도화준학솔.결과 본조환자중다발암적발생솔위0.55％,기중,쌍발암30례、삼발암2례,공66개원발조.32례다발암적66개원발조적SUVmax적평균치위6.68±3.61.PET/CT진단다발암원발조진양성위58개,가음성위8개.PET/CT진단다발암적령민도위87.9％,준학솔위87.9％.결론 18F-FDG PET/CT전신검사진단다발암구유교대개치.
Objective To explore the value of 18F-FDG PET/CT in diagnosis of multiple primary malignant neoplasms.Methods Five thousand eight hundred and twenty-two patients with suspected tumors were retrospectively reviewed.All cases underwent 18F-FDG PET/CT and 32 patients were confirmed with multiple primary malignancies by biopsy or resection.Mean standardized uptake value (SUVmean) was calculated and SUV ≥ 2.5 and abnormal morphological changes on CT were used as a standard to diagnose a malignant tumor.The sensitivity and accuracy of PET/CT in diagnosis of multiple primary maligant neoplasms were calculated.Results The incidence rate of multiple primary malignant neoplasms was 0.55％.Double primary malignant neoplasms were in 30 cases and triplicate primary malignant tumors were in 2 cases.There were 66 malignant tumor lesions.The average of SUVmean in 66 malignant tumor lesions was 6.68±3.61.The results of PET/CT were 58 true positive lesions and 8 false negative lesions.The sensitivity and accuracy of 18F-FDG PET/CT in diagnosis of multiple primary malignant neoplasms were 87.9％ and 87.9％ respectively.Conclusion 18F-FDG PET/CT whole body scan has an important value in the diagnosis of multiple primary malignant neoplasms.