CAJ | 학술논문

目的研究降钙素原(PCT)、C反应蛋白(CRP)在细菌性肺炎临床诊断价值.方法比较病毒、细菌、支原体引起的肺炎患者PCT、CRP血清浓度的变化情况及不同严重程度细菌性肺炎患者PCT、CRP的血清水平.结果三组CRP、PCT、WBC、NEUT经方差分析比较,差异有统计学意义(P＜0.05).CRP以细菌组升高幅度最大,支原体组次之；PCT以细菌组升高幅度最大,病毒组与支原体组升高不明显；细菌组中病情不同严重程度组别CRP、PCT、WBC经方差分析比较,差异有统计学意义(P＜0.05),CRP、PCT、WBC随病情严重程度依次升高.结论 PCT、CRP在细菌性肺炎的病原诊断、病情评估、预后判断上有重要临床应用价值.
목적 연구강개소원(PCT)、C반응단백(CRP)재세균성폐염림상진단개치.방법 비교병독、세균、지원체인기적폐염환자PCT、CRP혈청농도적변화정황급불동엄중정도세균성폐염환자PCT、CRP적혈청수평.결과 삼조CRP、PCT、WBC、NEUT경방차분석비교,차이유통계학의의(P＜0.05).CRP이세균조승고폭도최대,지원체조차지；PCT이세균조승고폭도최대,병독조여지원체조승고불명현；세균조중병정불동엄중정도조별CRP、PCT、WBC경방차분석비교,차이유통계학의의(P＜0.05),CRP、PCT、WBC수병정엄중정도의차승고.결론 PCT、CRP재세균성폐염적병원진단、병정평고、예후판단상유중요림상응용개치.
Objective To evaluate the clinical diagnostic value of procalcitonin (PCT),C-reactive protein (CRP) on bacterial pneumonia.Methods The difference of PCT and CRP concentration in serum of patients who were infected with virus,bacteria and mycoplasma was analyzed.Results There was statistical significance on CRP,PCT,WBC,NEUT among above-mentioned patients (P ＜0.05).The concentration of CRP increased at maximum in patients infected with bacteria,secondly in patients infected with mycoplasma.The PCT concentration increased at maximum in patients infected with bacteria,did not change in patients infected with virus or mycoplasm.There was statistical significance on CRP,PCT,WBC among different severity patients infected with bacteria (P ＜0.05).Conclusions PCT and CRP have a good clinical diagnostic value on pathogen diagnosis,disease severity and prognosis assessment of bacterial pneumonia.