国际呼吸杂志
國際呼吸雜誌
국제호흡잡지
INTERNATIONAL JOURNAL OF RESPIRATION
2013年
1期
12-14
,共3页
慢性阻塞性肺疾病%自主神经功能%心率变异性
慢性阻塞性肺疾病%自主神經功能%心率變異性
만성조새성폐질병%자주신경공능%심솔변이성
Chronic obstructive pulmonary disease%Autonomic nerve function%Heart rate variability
目的 探讨慢性阻塞性肺疾病急性加重(AECOPD)患者的自主神经功能的变化及其临床意义.方法 选择住院治疗的AECOPD患者51例及健康体检者53名,两组均行肺功能及24 h动态心电图检查,对比分析两组心率变异性时域分析结果差异.结果 AECOPD患者24 h动态心电图心率变异性时域分析各项评测指标(SDNN、SDANN、rMSSD和PNN50)结果分别为(123.82±78.95)、(90.06±40.99)、(80.37±53.88)和(8.00±9.35),正常对照组分别为(182.91±107.94)、(118.43±72.72)、(131.74±48.82)和(21.77±20.01),比较两组结果,差异均有统计学意义(P<0.05).结论 AECOPD患者存在自主神经功能损害,心率变异性时域分析各项评测指标能够较好反映AECOPD患者心率变异性变化,心率变异性分析有希望作为AECOPD临床监测的有价值指标.
目的 探討慢性阻塞性肺疾病急性加重(AECOPD)患者的自主神經功能的變化及其臨床意義.方法 選擇住院治療的AECOPD患者51例及健康體檢者53名,兩組均行肺功能及24 h動態心電圖檢查,對比分析兩組心率變異性時域分析結果差異.結果 AECOPD患者24 h動態心電圖心率變異性時域分析各項評測指標(SDNN、SDANN、rMSSD和PNN50)結果分彆為(123.82±78.95)、(90.06±40.99)、(80.37±53.88)和(8.00±9.35),正常對照組分彆為(182.91±107.94)、(118.43±72.72)、(131.74±48.82)和(21.77±20.01),比較兩組結果,差異均有統計學意義(P<0.05).結論 AECOPD患者存在自主神經功能損害,心率變異性時域分析各項評測指標能夠較好反映AECOPD患者心率變異性變化,心率變異性分析有希望作為AECOPD臨床鑑測的有價值指標.
목적 탐토만성조새성폐질병급성가중(AECOPD)환자적자주신경공능적변화급기림상의의.방법 선택주원치료적AECOPD환자51례급건강체검자53명,량조균행폐공능급24 h동태심전도검사,대비분석량조심솔변이성시역분석결과차이.결과 AECOPD환자24 h동태심전도심솔변이성시역분석각항평측지표(SDNN、SDANN、rMSSD화PNN50)결과분별위(123.82±78.95)、(90.06±40.99)、(80.37±53.88)화(8.00±9.35),정상대조조분별위(182.91±107.94)、(118.43±72.72)、(131.74±48.82)화(21.77±20.01),비교량조결과,차이균유통계학의의(P<0.05).결론 AECOPD환자존재자주신경공능손해,심솔변이성시역분석각항평측지표능구교호반영AECOPD환자심솔변이성변화,심솔변이성분석유희망작위AECOPD림상감측적유개치지표.
Objective To investigate the autonomic function and its clinical significance in patients with AECOPD.Methods 51 AECOPD in patients and 53 healthy persons were chosed.All patients were examined by the spirometry and 24 h Holter-monitoring electrocardiogram,followed by comparative analysis of the results of two sets of time,namely domain analysis.Results AECOPD patients 24 h ambulatory ECG heart rate variability time domain analysis results of the evaluation indicators (SDNN,SDANN,rMSSD,and PNN50) were (123.82±78.95),(90.06±40.99),(80.37±53.88),and (8.00±9.35),while normal control group (182.91± 107.94),(118.43 ± 72.72),(131.74 ± 48.82),and (21.77±20.01),respectively.Conclusions With two sets of results,differences were statistically significant (P <0.05).AECOPD patients exist autonomic nervous dysfunction.Heart rate variability time domain analysis of the evaluation index is in response to patients with AECOPD.It is promising to utilize the heart rate variability analysis as a valuable indicator for clinical monitoring AECOPD.