CAJ | 학술논문

随着肺癌的病因学研究进展,针对肺癌的药物研究也进入基因分子生物学时代.非小细胞肺癌的治疗提倡个体化治疗,即针对不同个体及致病基因,采用相应的分子靶向或化疗药物才能获得更大收益.本文总结了近年来关于非小细胞肺癌靶向基因和化疗的分子预测标志物以及相应药物的研究进展.
수착폐암적병인학연구진전,침대폐암적약물연구야진입기인분자생물학시대.비소세포폐암적치료제창개체화치료,즉침대불동개체급치병기인,채용상응적분자파향혹화료약물재능획득경대수익.본문총결료근년래관우비소세포폐암파향기인화화료적분자예측표지물이급상응약물적연구진전.
With the research advance of lung cancer etiology,the study of anti-cancer drug is stepping into an era of molecular biology of genes.Individualized therapy of non-small cell lung cancer (NSCLC) is emphasized,which means the patients will benefit more from using molecular targeted agents or chemotherapeutics according to individual patients and various disease-causing genes.In this article,the research progress of NSCLC targeting genes and chemotherapeutic molecular predictive biomarkers and corresponding drugs are summarized.