国际呼吸杂志
國際呼吸雜誌
국제호흡잡지
INTERNATIONAL JOURNAL OF RESPIRATION
2013年
3期
197-200
,共4页
金志贤%陈敏%杜俊毅%胡福定%毕虹
金誌賢%陳敏%杜俊毅%鬍福定%畢虹
금지현%진민%두준의%호복정%필홍
肺泡蛋白沉着症%全肺灌洗
肺泡蛋白沉著癥%全肺灌洗
폐포단백침착증%전폐관세
Pulmonary alveolar proteinosis%Whole lung lavage
目的 探讨大容量全肺灌洗治疗肺泡蛋白沉着症(pulmonary alveolar proteinosis,PAP),并观察其疗效.方法 对9例确诊PAP患者在全麻下行大容量全肺灌洗治疗,同时测定术前及术后1个月肺功能、血气分析、6分钟步行试验、Borg呼吸困难评分.结果 经全肺灌洗治疗后,8例患者的临床症状减轻,肺功能(FVC、FEV1、DLCO、MVV)、血气(PaO2、SaO2％)、6分钟步行试验、Borg呼吸困难评分均有显著改善；89％患者胸部高分辨率CT病灶有吸收.结论 全肺灌洗是目前治疗PAP安全有效的方法.
目的 探討大容量全肺灌洗治療肺泡蛋白沉著癥(pulmonary alveolar proteinosis,PAP),併觀察其療效.方法 對9例確診PAP患者在全痳下行大容量全肺灌洗治療,同時測定術前及術後1箇月肺功能、血氣分析、6分鐘步行試驗、Borg呼吸睏難評分.結果 經全肺灌洗治療後,8例患者的臨床癥狀減輕,肺功能(FVC、FEV1、DLCO、MVV)、血氣(PaO2、SaO2％)、6分鐘步行試驗、Borg呼吸睏難評分均有顯著改善；89％患者胸部高分辨率CT病竈有吸收.結論 全肺灌洗是目前治療PAP安全有效的方法.
목적 탐토대용량전폐관세치료폐포단백침착증(pulmonary alveolar proteinosis,PAP),병관찰기료효.방법 대9례학진PAP환자재전마하행대용량전폐관세치료,동시측정술전급술후1개월폐공능、혈기분석、6분종보행시험、Borg호흡곤난평분.결과 경전폐관세치료후,8례환자적림상증상감경,폐공능(FVC、FEV1、DLCO、MVV)、혈기(PaO2、SaO2％)、6분종보행시험、Borg호흡곤난평분균유현저개선；89％환자흉부고분변솔CT병조유흡수.결론 전폐관세시목전치료PAP안전유효적방법.
Objective To explore and observe the curative effect of large-capacity whole lung lavage for patients with pulmonary alveolar proteinosis.Methods Nine patients with pulmonary alveolar proteinosis were treated whole lung lavage under general anaesthesia,meanwhile respectively at preoperation and one month after operation measured the pulmonary function,blood gas analysis,six minutes walking test and Borg hard breath score.Results After whole lung lavage,eight patients' clinical symptoms relieved,and it was obvious that the patients had evidently improved in pulmonary function (FVC,FEVI,DLCO,MVV),blood gas analysis (PaO2,SaO2％),six minutes walking test and Borg hard breath score.Eighty-nine percent patients' focus absorbed in HRCT of chest.Conclusions At prsent whole lung lavage is a safe and effective kind of treatment for pulmonary alveolar proteinosis.
