CAJ | 학술논문

肺癌是最常见的恶性肿瘤,其发病率逐年上升.脑转移是肺癌最常见的转移部位之一,且有增加趋势,脑转移瘤如不治疗,中位生存期为1～3个月.肺癌脑转移以多发转移为主,常伴有颅内压迫症状,危及患者生命,严重影响生存质量.由于大多数化疗药物不能通过血脑屏障,既往放射治疗被认为是有效的治疗方法,但如今临床上很少单用一种治疗方法,而是采用综合治疗方法,如手术治疗联合化疗、手术治疗联合放疗、放化疗结合、靶向治疗等.本文就肺癌脑转移治疗进展作一综述.
폐암시최상견적악성종류,기발병솔축년상승.뇌전이시폐암최상견적전이부위지일,차유증가추세,뇌전이류여불치료,중위생존기위1～3개월.폐암뇌전이이다발전이위주,상반유로내압박증상,위급환자생명,엄중영향생존질량.유우대다수화료약물불능통과혈뇌병장,기왕방사치료피인위시유효적치료방법,단여금림상상흔소단용일충치료방법,이시채용종합치료방법,여수술치료연합화료、수술치료연합방료、방화료결합、파향치료등.본문취폐암뇌전이치료진전작일종술.
Lung cancer is regarded as the most common malignant tumor,Its incidence has been rising year by year.With a growing tendency,brain is the most common part for metastasis in lung cancer.The median survival time is 1-3 months if the metastatic encephaloma is not treated properly.Accompanied with the intracranial pressure,multiple metastases are in the majorority of the lung cancer with brain metastasis which endangers the patients' lives and has a serious affect on the quality of life.Since the blood and brain can make a barrier which most drugs for chemotherapy can not therapy.But now,it is rare in clinic that only one kind of therapy is applied in treatment,The common situation is that the comprehensive therapies are adopted,such as surgery combined with chemotherapy,surgery combined with radiotherapy,chemotherapy,targeted therapy,etc.The recent progress achieved in the therapies of lung cancer with brain metastasis is summarized in this paper.