国际呼吸杂志
國際呼吸雜誌
국제호흡잡지
INTERNATIONAL JOURNAL OF RESPIRATION
2014年
1期
21-26
,共6页
经支气管镜肺减容术%慢性阻塞性肺疾病%治疗%研究进展
經支氣管鏡肺減容術%慢性阻塞性肺疾病%治療%研究進展
경지기관경폐감용술%만성조새성폐질병%치료%연구진전
Bronchoscopic lung volume reduction%Chronic obstructive pulmonary disease%Treatment%Advance
目的 综述经支气管镜肺减容术(bronchoscopic lung volume reduction,BLVR)治疗COPD的最新临床报道和研究进展,为COPD的临床治疗和研究思路提供更多的选择.方法 对近20年来国内外发表的相关文献进行整理、分析和归纳.结果 BLVR是根据肺减容术(lung volume reduction surgery,LVRS)原理,不需行开胸术,利用支气管镜完成肺减容的微创技术.目前常用的方法有支气管封堵法和支气管开窗法.其目的都是获得LVRS益处,而减少手术创伤、风险及长期的康复过程.结论 BLVR是一种无须开胸、创伤性小的新治疗方法,在临床上大大降低了潜在的病死率和发病率,展现了巨大的临床应用前景.但由于目前还缺少大规模的随机对照临床试验结果,一些方法还处于动物实验阶段,缺乏临床研究,尚处于起步阶段.
目的 綜述經支氣管鏡肺減容術(bronchoscopic lung volume reduction,BLVR)治療COPD的最新臨床報道和研究進展,為COPD的臨床治療和研究思路提供更多的選擇.方法 對近20年來國內外髮錶的相關文獻進行整理、分析和歸納.結果 BLVR是根據肺減容術(lung volume reduction surgery,LVRS)原理,不需行開胸術,利用支氣管鏡完成肺減容的微創技術.目前常用的方法有支氣管封堵法和支氣管開窗法.其目的都是穫得LVRS益處,而減少手術創傷、風險及長期的康複過程.結論 BLVR是一種無鬚開胸、創傷性小的新治療方法,在臨床上大大降低瞭潛在的病死率和髮病率,展現瞭巨大的臨床應用前景.但由于目前還缺少大規模的隨機對照臨床試驗結果,一些方法還處于動物實驗階段,缺乏臨床研究,尚處于起步階段.
목적 종술경지기관경폐감용술(bronchoscopic lung volume reduction,BLVR)치료COPD적최신림상보도화연구진전,위COPD적림상치료화연구사로제공경다적선택.방법 대근20년래국내외발표적상관문헌진행정리、분석화귀납.결과 BLVR시근거폐감용술(lung volume reduction surgery,LVRS)원리,불수행개흉술,이용지기관경완성폐감용적미창기술.목전상용적방법유지기관봉도법화지기관개창법.기목적도시획득LVRS익처,이감소수술창상、풍험급장기적강복과정.결론 BLVR시일충무수개흉、창상성소적신치료방법,재림상상대대강저료잠재적병사솔화발병솔,전현료거대적림상응용전경.단유우목전환결소대규모적수궤대조림상시험결과,일사방법환처우동물실험계단,결핍림상연구,상처우기보계단.
Objective Through summarizing the clinical advance of bronchoscopic lung volume reduction (BLVR)in treating chronic obstructive pulmonary disease (COPD),to provide more choices for the clinical treatment and research idea of COPD.Methods The related references in recent 20 years at home and abroad were collected,summarized and analyzed.Results BLVR was an minimally invasive technique with bronchoscopic to achieve lung volume reduction,which was no need thoracotomy according to the lung volume reduction surgery (LVRS) principle.The commonly used methods were bronchus blocking method and bronchial fenestration.Its purpose was to obtain LVRS benefits,and reduce the surgical trauma,risk and long-term rehabilitation process.Conclusions BLVR was a new treatment method with no need thoracotomy and small surgical trauma.In clinic,it reduced greatly the potential mortality and morbidity,and showed great clinical application prospect.But due to the lack of large-scale randomized controlled clinical trials,some methods were still in the animal experiment stage and lack of clinical research,so BLVR was still in its infancy.
