国际呼吸杂志
國際呼吸雜誌
국제호흡잡지
INTERNATIONAL JOURNAL OF RESPIRATION
2014年
3期
196-199
,共4页
支气管舒张试验%肺功能指标%诊断价值
支氣管舒張試驗%肺功能指標%診斷價值
지기관서장시험%폐공능지표%진단개치
Bronchodilatation test%Pulmonary function standards%Diagnostic value
目的 研究相关肺功能指标在支气管舒张试验中的诊断价值.方法 收集北京大学第三医院门诊肺功能室1044例患者的肺功能资料,以临床常用标准FEV1标准为参照,评估FVC,呼气峰流速(PEF),用力呼气流速25％-75％(FEF25％-75％)对支气管舒张试验的诊断价值.结果 应用支气管舒张剂后,FEV1,FVC,PEF,FEF25％-75％的阳性率分别为26.7％,21.8％,21.8％,34.0％,以FEV1标准为参照,FVC,PEF,FEF25 ％％-75％等三项标准的灵敏度分别为53.0％,49.5％,97.8％,特异度分别为89.5％,88.2％,83.8％,阳性预测值分别为64.9％,60.5％,68.8％,阴性预测值分别为83.9％,82.7％,99.1％,ROC曲线下面积分别为0.866,0.798,0.979,Kappa值分别为0.45,0.40,0.72.结论 支气管舒张试验应以FEV1作为主要标准,并联合其他多项肺功能指标及临床资料加以综合评价.
目的 研究相關肺功能指標在支氣管舒張試驗中的診斷價值.方法 收集北京大學第三醫院門診肺功能室1044例患者的肺功能資料,以臨床常用標準FEV1標準為參照,評估FVC,呼氣峰流速(PEF),用力呼氣流速25％-75％(FEF25％-75％)對支氣管舒張試驗的診斷價值.結果 應用支氣管舒張劑後,FEV1,FVC,PEF,FEF25％-75％的暘性率分彆為26.7％,21.8％,21.8％,34.0％,以FEV1標準為參照,FVC,PEF,FEF25 ％％-75％等三項標準的靈敏度分彆為53.0％,49.5％,97.8％,特異度分彆為89.5％,88.2％,83.8％,暘性預測值分彆為64.9％,60.5％,68.8％,陰性預測值分彆為83.9％,82.7％,99.1％,ROC麯線下麵積分彆為0.866,0.798,0.979,Kappa值分彆為0.45,0.40,0.72.結論 支氣管舒張試驗應以FEV1作為主要標準,併聯閤其他多項肺功能指標及臨床資料加以綜閤評價.
목적 연구상관폐공능지표재지기관서장시험중적진단개치.방법 수집북경대학제삼의원문진폐공능실1044례환자적폐공능자료,이림상상용표준FEV1표준위삼조,평고FVC,호기봉류속(PEF),용력호기류속25％-75％(FEF25％-75％)대지기관서장시험적진단개치.결과 응용지기관서장제후,FEV1,FVC,PEF,FEF25％-75％적양성솔분별위26.7％,21.8％,21.8％,34.0％,이FEV1표준위삼조,FVC,PEF,FEF25 ％％-75％등삼항표준적령민도분별위53.0％,49.5％,97.8％,특이도분별위89.5％,88.2％,83.8％,양성예측치분별위64.9％,60.5％,68.8％,음성예측치분별위83.9％,82.7％,99.1％,ROC곡선하면적분별위0.866,0.798,0.979,Kappa치분별위0.45,0.40,0.72.결론 지기관서장시험응이FEV1작위주요표준,병연합기타다항폐공능지표급림상자료가이종합평개.
Objective To evaluate the diagnostic value of various pulmonary function standards of diagnosing on bronchodilation test.Methods The lung function test results of 1 044 patients in Peking university third hospital were collected,and compared with FEV1 criterion as reference,the diagnostic value of FVC,PEF and FEF25％-75％ on bronchodilation test were estimated.Results The positive rate of FEV1,FVC,PEF and FEF25％-75％ were respectively 26.7％,21.8％,21.8％ and 34.0％.Jarging by FEV1 as objective reference,the sensitivity of FVC,PEF and FEF25％-75％ were 53.0％,49.5％ and 97.8％ respectively,the specificity of them were 89.5 ％,88.2 ％ and 83.8 ％,the positive predictive value of them were 64.9％,60.5％,68.8％,the negative predictive value of them were 83.9％,82.7％,99.1％,the area under the ROC curve of them were separately 0.866,0.798 and 0.979,and the Kappa statistic of FVC,PEF and FEF25％-75％ were 0.45,0.40 and 0.72 respectively.Conclusions FEV1 should be used as the primary standard in assessing bronchodilator reversibility,and other standards and clinical features are also important for evaluating the results of bronchodilatation test.
