CAJ | 학술논문

肺癌肿瘤局部浸润的免疫细胞、间质细胞及所分泌的活性介质等与肺癌细胞共同构成的局部内环境又被称之为肺癌微环境.肺癌微环境中浸润的免疫细胞参与了肺癌的疾病进展和免疫逃逸.本文对这一群细胞的浸润特征、功能和相互关系进行阐述,探讨其在肺癌发生发展过程中的作用.
폐암종류국부침윤적면역세포、간질세포급소분비적활성개질등여폐암세포공동구성적국부내배경우피칭지위폐암미배경.폐암미배경중침윤적면역세포삼여료폐암적질병진전화면역도일.본문대저일군세포적침윤특정、공능화상호관계진행천술,탐토기재폐암발생발전과정중적작용.
The lung tumor microenvironment includes local infiltration of immune cells,mesenchymal cells,cytokines and lung cancer cells.The infiltration of immune cells in the lung tumor microenvironment is involved in lung cancer progression and immune escape.This article discusses infiltration characteristics,function,and relationship of these cells,explores the role of tumor microenvironment in process and development of lung cancer.