CAJ | 학술논문

微囊(caveolae)是存在于细胞膜上烧瓶样的内陷微结构,它参与细胞的众多生命活动,如细胞的内吞作用、胆固醇代谢、肿瘤的发生以及信号转导过程.微囊蛋白-1(caveolin-1)是caveolae最重要的结构蛋白,研究表明许多呼吸系统疾病与caveolin-1的表达异常密切相关,本文就其在支气管哮喘中的研究进展作一综述.
미낭(caveolae)시존재우세포막상소병양적내함미결구,타삼여세포적음다생명활동,여세포적내탄작용、담고순대사、종류적발생이급신호전도과정.미낭단백-1(caveolin-1)시caveolae최중요적결구단백,연구표명허다호흡계통질병여caveolin-1적표체이상밀절상관,본문취기재지기관효천중적연구진전작일종술.
Caveolae are micro structures which form flask-shaped invaginations of the plasma membrane,caveolae are involved in many life activities of the cells,such as endocytosis,cholesterol metabolism,tumorigenesis and the process of signal transduction.Caveolin-1 is the most important structural protein of caveolae,studies have shown that many respiratory diseases is closely related to the abnormal of caveolin-1.Here,we introduce the research progress of caveolin-1 in bronchial asthma.