CAJ | 학술논문

目的探讨恶性胸膜间皮瘤(MPM)的临床特点、诊断及治疗.方法报告2013年2月甘肃省人民医院呼吸科收治的1例青年MPM病例及相关内容综述.结果患者,男,20岁,否认石棉接触史,咳嗽、气短2周,胸片提示左侧大量胸腔积液.引流胸水10 000 ml后复查胸部CT示左侧胸腔内低密度肿块影,行胸膜穿刺活检,病理结果为:MPM(腺管乳头状型).结合此例患者特点和文献复习,青年MPM患者少见,可仅表现为胸腔积液,亦可无任何临床表现.结论 MPM属高度侵袭性肿瘤,临床表现缺乏特异性,可发生于任何年龄,亦可无石棉接触史,需提高对该疾病的认识及诊断水平,以便早期诊断、早期治疗,提高患者生存质量及生存期.
목적 탐토악성흉막간피류(MPM)적림상특점、진단급치료.방법 보고2013년2월감숙성인민의원호흡과수치적1례청년MPM병례급상관내용종술.결과 환자,남,20세,부인석면접촉사,해수、기단2주,흉편제시좌측대량흉강적액.인류흉수10 000 ml후복사흉부CT시좌측흉강내저밀도종괴영,행흉막천자활검,병리결과위:MPM(선관유두상형).결합차례환자특점화문헌복습,청년MPM환자소견,가부표현위흉강적액,역가무임하림상표현.결론 MPM속고도침습성종류,림상표현결핍특이성,가발생우임하년령,역가무석면접촉사,수제고대해질병적인식급진단수평,이편조기진단、조기치료,제고환자생존질량급생존기.
Objective To discuss the clinical features,diagnosis,and treatment of malignant pleural mesothelioma (MPM).Methods One young case of MPM treated in the department of respiratory medicine,Gansu provincial people's hospital in February 2013 was reported and related literatures were reviewed.Results The male patient,20 years old,denied the history of asbestos exposure,had cough and shortness of breath for more than two weeks.Chest X-ray showed large pleural effusion in the left.After the drainage of pleural effusion for 10 000 ml,chest CT showed low-density mass in the left chest.After pleural biopsy,pathology result showed MPM (tubular papillary variant).Combined with the characteristics of this patient and review of the literatures,young patients with MPM were rare,characterized with only pleural effusion,or without any clinical manifestations.Conclusions MPM is a highly aggressive tumor,lacking of specific clinical manifestations.It can not only occur at any age,but also have no history of asbestos exposure.It should be emphasized to raise awareness of the disease for early diagnosis and early treatment in order to improve the quality of life and survival of patients.