CAJ | 학술논문

支气管扩张是慢性气道损伤引起支气管管壁肌肉和弹力支撑组织破坏所导致的一组支气管不可逆性扩张.其发病率在3.9/10万到52/10万左右,不发达国家发病率相对较高.在我国,支气管扩张被当做气道的一般化脓性炎症来治疗,但其病因、发病机制、针对性的治疗手段均研究甚少.文中结合目前的文献及2010年英国胸科学会的支气管扩张诊治指南,对非囊性纤维化性支气管扩张的诊治最新进展作简要述评.
지기관확장시만성기도손상인기지기관관벽기육화탄력지탱조직파배소도치적일조지기관불가역성확장.기발병솔재3.9/10만도52/10만좌우,불발체국가발병솔상대교고.재아국,지기관확장피당주기도적일반화농성염증래치료,단기병인、발병궤제、침대성적치료수단균연구심소.문중결합목전적문헌급2010년영국흉과학회적지기관확장진치지남,대비낭성섬유화성지기관확장적진치최신진전작간요술평.
Bronchiectasis is a kind of irreversible bronchial dilation,which is caused by damage of bronchial wall muscle and elastic supporting tissue induced by chronic airway destruction.The worldwide incidence rate of bronchiectasis is 3.9/100 000 to 52/100 000,and the incidence rate in the developing country is relatively higher.In China,bronchiectasis is usually treated as purulent inflammation of the airway.However the studies on etiology,pathogenesis and targeted therapeutic method of bronchiectasis were limited.In this review,we studied current literature on bronchiectasis and combined with the diagnosis and treatment guideline for bronchiectasis from the British Thoracic Society in 2010 to briefly introduce the latest progress on the diagnosis and treatment of non-cystic fibrosis bronchiectasis.