CAJ | 학술논문

目的对36例局灶性磨玻璃影(focal ground-glass opacity,fGGO)患者各项临床资料进行分析,以便提高对fGGO的认识.方法回顾性分析了36例fGGO患者,根据病理分为良性病灶、癌前病灶和恶性病灶,对比各组临床表现、影像学表现及实验室、病理检查结果间差异.结果 36例fGGO中,混合性磨玻璃影23例,单纯性磨玻璃影13例;恶性15例,癌前病变12例,良性9例.各组年龄及性别差异无统计学意义.分析各组病灶直径及磨玻璃比例,恶性病灶组直径最大,其次是良性病灶,癌前病灶组直径最小;但磨玻璃比例在恶性组最低,癌前病变组最高,良性组介于两者之间.病灶直径及磨玻璃比例三组间均有显著性的差异.恶性磨玻璃影多呈类圆形,实性成分边界及磨玻璃边界多清晰,磨玻璃和实性成分多有分叶、毛刺征;癌前病变病灶多呈类圆形,边界清晰;良性病灶形态多不规则,可有长毛刺,磨玻璃影边界多模糊.结论持续存在半年以上的fGGO病灶直径越大、实性成分越多,其恶性疾病可能性越大.
목적 대36례국조성마파리영(focal ground-glass opacity,fGGO)환자각항림상자료진행분석,이편제고대fGGO적인식.방법 회고성분석료36례fGGO환자,근거병리분위량성병조、암전병조화악성병조,대비각조림상표현、영상학표현급실험실、병리검사결과간차이.결과 36례fGGO중,혼합성마파리영23례,단순성마파리영13례;악성15례,암전병변12례,량성9례.각조년령급성별차이무통계학의의.분석각조병조직경급마파리비례,악성병조조직경최대,기차시량성병조,암전병조조직경최소;단마파리비례재악성조최저,암전병변조최고,량성조개우량자지간.병조직경급마파리비례삼조간균유현저성적차이.악성마파리영다정류원형,실성성분변계급마파리변계다청석,마파리화실성성분다유분협、모자정;암전병변병조다정류원형,변계청석;량성병조형태다불규칙,가유장모자,마파리영변계다모호.결론 지속존재반년이상적fGGO병조직경월대、실성성분월다,기악성질병가능성월대.
Objective To improve our recognition of focal ground-glass opacity (GGO) by analyzing clinical data of 36 patients.Methods Thirty six patients were distributed into benign lesion group,precancerous lesion group,and malignant lesion group.The clinical manifestations,computed tomography features,and laboratory test and pathology results were retrospectively analyzed.Results Among 36 focal GGO nodules (23 cases of mixed GGO and 13 cases of pure GGO),15 malignant lesions,12 pre-malignant lesions,and nine benign nodules were determined respectively.There were no statistical differences in age and sex ratio among three groups.The average size of nodules was the largest in the malignant group followed by benign group and precancerous lesion group.On the contrary,the ratio of GGO was the highest in the precancerous lesion group followed by benign group and malignant group.Most malignant GGO exhibited round shape,along with well-defined but coarse interface,lobulation and spiculated border for solid and GGO component.Similarly,GGO from precancerous lesion group mainly showed round shape and well-defined border.Furthermore,GGO with polygonal shape and long speculated and ill-defined margins were frequently shown in benign group.Conclusions The larger size and higher percent of solid component are in focal GGO for over six months,the higher probability of malignancy is.