国际呼吸杂志
國際呼吸雜誌
국제호흡잡지
INTERNATIONAL JOURNAL OF RESPIRATION
2014年
20期
1580-1583
,共4页
白介素35%抑制性细胞因子%炎症性疾病
白介素35%抑製性細胞因子%炎癥性疾病
백개소35%억제성세포인자%염증성질병
Interleukin-35%Inhibitory cytokines%Inflammatory disease
IL-35是一种抑制性细胞因子,属于IL-12细胞因子家族的新成员,它是由调节性T细胞结构性分泌产生,由P35和EBI3两个亚基组成.研究发现,IL-35在自身免疫性疾病、炎症性疾病、肿瘤等治疗中有重要作用.在临床上,感染性疾病的控制一直是个难题,IL-35的应用也许为临床提供一种新的思路和方法.
IL-35是一種抑製性細胞因子,屬于IL-12細胞因子傢族的新成員,它是由調節性T細胞結構性分泌產生,由P35和EBI3兩箇亞基組成.研究髮現,IL-35在自身免疫性疾病、炎癥性疾病、腫瘤等治療中有重要作用.在臨床上,感染性疾病的控製一直是箇難題,IL-35的應用也許為臨床提供一種新的思路和方法.
IL-35시일충억제성세포인자,속우IL-12세포인자가족적신성원,타시유조절성T세포결구성분비산생,유P35화EBI3량개아기조성.연구발현,IL-35재자신면역성질병、염증성질병、종류등치료중유중요작용.재림상상,감염성질병적공제일직시개난제,IL-35적응용야허위림상제공일충신적사로화방법.
Interleukin-35 (IL-35) is an inhibitory cytokine.It belongs to the new member of IL-12 cytokine family cluster.It is produced by regulatory T cells structural secretion.IL-35 is a heterodimer consisting of P35 and EBI3 subunits.The studies have found that IL-35 plays an important role in the treatment of autoimmune diseases,inflammatory diseases,cancer and so on.In clinic,the control of infectious disease is always a difficult problem.The application of IL-35 may provide a new thought and method for clinician.
