CAJ | 학술논문

肠道病毒是人类感染率很高的一种病毒,其衣壳蛋白在病毒的致病性方面起着重要的作用.近年来,大量的研究工作致力于肠道病毒农壳蛋白的致病性研究.此文就衣壳蛋白的基因组结构、基因分型、与病毒受体的相互作用和疫苗研制等方面作了综述.
장도병독시인류감염솔흔고적일충병독,기의각단백재병독적치병성방면기착중요적작용.근년래,대량적연구공작치력우장도병독농각단백적치병성연구.차문취의각단백적기인조결구、기인분형、여병독수체적상호작용화역묘연제등방면작료종술.
The capsid proteins of enterovirus which have a high infection rate in humans play an important role in the virus pathopoiesis.Recently,considerable efforts have been made in the pathogenicity research of enterovirus capsid proteins.In this article,the current knowledge concerning the genome organization,genomic typing,the capsid binding molecules and the potential vaccine strategy targeting the viral capsid proteins are reviewed.