CAJ | 학술논문

近十年来妊娠梅毒和先天梅毒的发病率呈上升趋势.未经治疗的孕妇可将梅毒传染给胎儿,引起生长受限、肝肿大、血液与转氨酶异常,进而导致早产、死产、先天梅毒.早期先天梅毒以皮肤、脏器炎症反应为主;晚期先天梅毒,主要是慢性炎症导致的畸形.对妊娠梅毒患者的及时诊断和治疗可有效避免先天梅毒的发生.此文对妊娠梅毒和先天梅毒的临床特征、诊断、治疗及随访做一综述,以期为临床工作提供参考.
근십년래임신매독화선천매독적발병솔정상승추세.미경치료적잉부가장매독전염급태인,인기생장수한、간종대、혈액여전안매이상,진이도치조산、사산、선천매독.조기선천매독이피부、장기염증반응위주;만기선천매독,주요시만성염증도치적기형.대임신매독환자적급시진단화치료가유효피면선천매독적발생.차문대임신매독화선천매독적림상특정、진단、치료급수방주일종술,이기위림상공작제공삼고.
Morbidity of syphilis in pregnancy and congenital syphilis has been rising during the past ten years.Untreated syphilis infection can infect fetus and leads to adverse pregnancy outcomes,including growth resriction,hepatomegaly,blood and transaminase disorder,and then premature birth,stillbirth and congenital syphilis.Early congenital syphilis presents with cutaneous covering and organ inflammatory reaction.Late congenital syphilis presents with anisotrophy causing by chronic inflammation.Timely diagnosis and treatment syphilis in pregnancy can avoid the incidence of congenital syphilis.The clinical characters,diagnosis,treatment and follow-up visit of syphilis in pregnancy and congenital syphilis are reviewed in this article,so as to provide reference for clinical practice.