CAJ | 학술논문

目的调查济南市职工慢性肾脏病(CKD)的患病情况及危险因素.方法回顾性分析2007年2月～2011年5月在本院体检中心进行首次体检的成人的体检资料,分析其CKD的患病率及危险因素.结果在资料完整的10016例体检者中,血尿患病率为4.20％(95％CI为3.81％～4.59％),蛋白尿患病率为0.70％(95％CI为0.54％～0.86％),肾功能下降率为2.09％(95％CI为1.81％～ 2.37％),CKD患病率为6.37％(95％CI为5.89％～ 6.85％).经二分类非条件Logistic回归分析,女性是血尿发生的独立危险因素.高血压、糖尿病是蛋白尿发生的独立危险因素.性别、年龄和肥胖是肾功能下降的独立危险因素.性别、年龄、肾囊肿和糖尿病是CKD的独立危险因素(P≤0.05).结论性别、年龄、肾囊肿和糖尿病是CKD的独立危险因素,对于CKD,应加强在高危人群中的筛查,做到早发现、早干预,延缓CKD的进展,防止ESRD和CVD的发生,减轻社会及家庭的负担.
목적 조사제남시직공만성신장병(CKD)적환병정황급위험인소.방법 회고성분석2007년2월～2011년5월재본원체검중심진행수차체검적성인적체검자료,분석기CKD적환병솔급위험인소.결과 재자료완정적10016례체검자중,혈뇨환병솔위4.20％(95％CI위3.81％～4.59％),단백뇨환병솔위0.70％(95％CI위0.54％～0.86％),신공능하강솔위2.09％(95％CI위1.81％～ 2.37％),CKD환병솔위6.37％(95％CI위5.89％～ 6.85％).경이분류비조건Logistic회귀분석,녀성시혈뇨발생적독립위험인소.고혈압、당뇨병시단백뇨발생적독립위험인소.성별、년령화비반시신공능하강적독립위험인소.성별、년령、신낭종화당뇨병시CKD적독립위험인소(P≤0.05).결론 성별、년령、신낭종화당뇨병시CKD적독립위험인소,대우CKD,응가강재고위인군중적사사,주도조발현、조간예,연완CKD적진전,방지ESRD화CVD적발생,감경사회급가정적부담.
Objectives To investigate the prevalence and risk factors of chronic kidney disease(CKD)in the adult staff receiving physical examination in Jinan.Methods A retrospective analysis on the first examination data of the healthy adult,analyzing the prevalence of CKD and its risk factors,from February 2007 to May 2011.Results In the total 10016 healthy persons,the prevalence of hematuresis was 4.20％(95％CI:3.81％～4.59％),the Prevalence of proteinuria was 0.70％(95 ％ CI:0.54 ％～ 0.86 ％),reduced eGFR was 2.09 ％(95 ％ CI: 1.81％～2.37％),the prevalence of CKD was 6.37％(95 ％ CI:5.89 ％～ 6.85 ％).After the two categories of non-conditional Logistic regression analysis,female is independently risk factor for hematuria.Hypertension and diabetes are risk factors for albuminuria.Gender,age and obesity are independently associated with reduced eGFR.Gender,age,renal cysts and diabetes are independently risk factors for CKD(P ≤ 0.05).Conclusions Gender,age,renal cysts and diabetes are independently associated with CKD.The high-risk groups of CKD should be strengthened in the screening,so early detection and intervention could help to delay the progress of CKD and prevent the occurrence of ESRD and CVD.