国际泌尿系统杂志
國際泌尿繫統雜誌
국제비뇨계통잡지
INTERNATIONAL JOURNAL OF UROLOGY AND NEPHROLOGY
2013年
2期
171-174
,共4页
牛铁明%熊焰%栾迅飞%刘炎
牛鐵明%熊燄%欒迅飛%劉炎
우철명%웅염%란신비%류염
肾透析%腹膜透析%炎症%营养状况%心血管疾病
腎透析%腹膜透析%炎癥%營養狀況%心血管疾病
신투석%복막투석%염증%영양상황%심혈관질병
Renal Dialysis%Peritoneal Dialysis%Inflammation%Nutritional Status%Cardiovascular Diseases
目的 研究血液透析、腹膜透析两种透析方式对慢性肾衰尿毒症患者微炎症状态的影响,探讨微炎症状态与营养状况、心血管疾病的关系.方法 选择2011年1月至2012年6月沈阳市红十字会医院肾内科住院的尿毒症患者64例(血液透析30例、腹膜透析34例)及健康对照者30例,检测C反应蛋白、白介素6、尿素氮、肌酐、白蛋白、前白蛋白、血红蛋白,计算体重指数.根据主观综合性营养评价将患者分为营养良好组、营养不良组.记录透析处方和心血管并发症.结果 本组尿毒症患者C反应蛋白、白介素6较对照组显著升高(P＜0.01),血液透析组C反应蛋白、白介素6显著高于腹膜透析组(P＜0.05).尿毒症各组内营养良好组C反应蛋白、白介素6较营养不良组显著升高(P＜0.05),合并慢性心衰组C反应蛋白、白介素6较无心衰并发症组显著升高(P＜0.05).C反应蛋白与白蛋白、前白蛋白呈显著负相关,与尿素氮、肌酐、血红蛋白无显著相关性.结论 血液透析患者微炎症状态比腹膜透析患者严重,尿毒症患者微炎症状态与营养不良及心血管疾病密切相关.
目的 研究血液透析、腹膜透析兩種透析方式對慢性腎衰尿毒癥患者微炎癥狀態的影響,探討微炎癥狀態與營養狀況、心血管疾病的關繫.方法 選擇2011年1月至2012年6月瀋暘市紅十字會醫院腎內科住院的尿毒癥患者64例(血液透析30例、腹膜透析34例)及健康對照者30例,檢測C反應蛋白、白介素6、尿素氮、肌酐、白蛋白、前白蛋白、血紅蛋白,計算體重指數.根據主觀綜閤性營養評價將患者分為營養良好組、營養不良組.記錄透析處方和心血管併髮癥.結果 本組尿毒癥患者C反應蛋白、白介素6較對照組顯著升高(P＜0.01),血液透析組C反應蛋白、白介素6顯著高于腹膜透析組(P＜0.05).尿毒癥各組內營養良好組C反應蛋白、白介素6較營養不良組顯著升高(P＜0.05),閤併慢性心衰組C反應蛋白、白介素6較無心衰併髮癥組顯著升高(P＜0.05).C反應蛋白與白蛋白、前白蛋白呈顯著負相關,與尿素氮、肌酐、血紅蛋白無顯著相關性.結論 血液透析患者微炎癥狀態比腹膜透析患者嚴重,尿毒癥患者微炎癥狀態與營養不良及心血管疾病密切相關.
목적 연구혈액투석、복막투석량충투석방식대만성신쇠뇨독증환자미염증상태적영향,탐토미염증상태여영양상황、심혈관질병적관계.방법 선택2011년1월지2012년6월침양시홍십자회의원신내과주원적뇨독증환자64례(혈액투석30례、복막투석34례)급건강대조자30례,검측C반응단백、백개소6、뇨소담、기항、백단백、전백단백、혈홍단백,계산체중지수.근거주관종합성영양평개장환자분위영양량호조、영양불량조.기록투석처방화심혈관병발증.결과 본조뇨독증환자C반응단백、백개소6교대조조현저승고(P＜0.01),혈액투석조C반응단백、백개소6현저고우복막투석조(P＜0.05).뇨독증각조내영양량호조C반응단백、백개소6교영양불량조현저승고(P＜0.05),합병만성심쇠조C반응단백、백개소6교무심쇠병발증조현저승고(P＜0.05).C반응단백여백단백、전백단백정현저부상관,여뇨소담、기항、혈홍단백무현저상관성.결론 혈액투석환자미염증상태비복막투석환자엄중,뇨독증환자미염증상태여영양불량급심혈관질병밀절상관.
Objectives To study the influence of the two kinds of dialysis to microinfectian and the relationship among microinfection,malnutrition and cardiovascular diseases.Methods 34 clinically stable continuous peritonealdialysis (PD) patients and 30 blood hemodialysis (HD) patients were investigated.Serum interleukin-6 (IL-6) and Creative protein (CRP)were measured as markers of chronic inflammation,the serumalbumin (Alb),prealbumin(PA),hemoglobin(Hb) were measured before hemodialysis,subjective global assessment(SGA) was also evaluated.Cardiovascular disease and dialysis regime were investigated,too.Results HD patients inflectional indexes are significantly higher than PD patients (CRP and IL-6,P ＜ 0.05) ;The concentrations of CRP and IL-6 were significantly elevated in malnourished group compared to the nourished group (P ＜ 0.05).The patients with chronic heart failure had higher CRP and IL-6 levels than whose without above complications(P ＜ 0.05).The CRP level of patients were negatively correlated with Alb and PA.Conclusions HD patients infection is more serious than PD's and infection is associated with malnutrition and cardiovascular disease.
