国际泌尿系统杂志
國際泌尿繫統雜誌
국제비뇨계통잡지
INTERNATIONAL JOURNAL OF UROLOGY AND NEPHROLOGY
2014年
2期
215-218
,共4页
肾疾病%肾替代疗法
腎疾病%腎替代療法
신질병%신체대요법
Kidney Disease%Renal Replacement Therapy
目的 探索急性肾损伤(AKI)的非肾脏替代治疗(非RRT)疗法.方法 对97例AKI分别采用ABC其中一种非RRT疗法.A疗法是随机分组治疗60例,其中治疗组32例用前列地尔(PGE1)联合甘露醇及呋塞米序贯治疗,对照组28例予小剂量多巴胺联合呋塞米治疗;B疗法是肾康注射液(SKI)治疗24例;C疗法是PGE1和SKI联合甘露醇或呋塞米序贯治疗13例.结果 A疗法总有效率80.0％ (48/60),治疗组的治愈率及总有效率均优于对照组(P＜0.05);B疗法有效率79.2％ (19/24);C疗法有效率100％(13/13).全部97例中非RRT治愈或好转80例(82.5％),需RRT 17例(17.5％),两者比较差异有统计学意义(P＜0.01).结论 ①大部分AKI都可经药物治疗成功,需RRT的仅是少数;②由PGE1联合甘露醇及呋塞米序贯或SKI单独或这几种药搭配序贯组成的非RRT对AKI都有较好的疗效;③治疗成功的关键是早诊断、早治疗.
目的 探索急性腎損傷(AKI)的非腎髒替代治療(非RRT)療法.方法 對97例AKI分彆採用ABC其中一種非RRT療法.A療法是隨機分組治療60例,其中治療組32例用前列地爾(PGE1)聯閤甘露醇及呋塞米序貫治療,對照組28例予小劑量多巴胺聯閤呋塞米治療;B療法是腎康註射液(SKI)治療24例;C療法是PGE1和SKI聯閤甘露醇或呋塞米序貫治療13例.結果 A療法總有效率80.0％ (48/60),治療組的治愈率及總有效率均優于對照組(P＜0.05);B療法有效率79.2％ (19/24);C療法有效率100％(13/13).全部97例中非RRT治愈或好轉80例(82.5％),需RRT 17例(17.5％),兩者比較差異有統計學意義(P＜0.01).結論 ①大部分AKI都可經藥物治療成功,需RRT的僅是少數;②由PGE1聯閤甘露醇及呋塞米序貫或SKI單獨或這幾種藥搭配序貫組成的非RRT對AKI都有較好的療效;③治療成功的關鍵是早診斷、早治療.
목적 탐색급성신손상(AKI)적비신장체대치료(비RRT)요법.방법 대97례AKI분별채용ABC기중일충비RRT요법.A요법시수궤분조치료60례,기중치료조32례용전렬지이(PGE1)연합감로순급부새미서관치료,대조조28례여소제량다파알연합부새미치료;B요법시신강주사액(SKI)치료24례;C요법시PGE1화SKI연합감로순혹부새미서관치료13례.결과 A요법총유효솔80.0％ (48/60),치료조적치유솔급총유효솔균우우대조조(P＜0.05);B요법유효솔79.2％ (19/24);C요법유효솔100％(13/13).전부97례중비RRT치유혹호전80례(82.5％),수RRT 17례(17.5％),량자비교차이유통계학의의(P＜0.01).결론 ①대부분AKI도가경약물치료성공,수RRT적부시소수;②유PGE1연합감로순급부새미서관혹SKI단독혹저궤충약탑배서관조성적비RRT대AKI도유교호적료효;③치료성공적관건시조진단、조치료.
Objectives To explore the therapy that non renal replacement treatment (non RRT) in acute kidney injury (AKI).Methods 97 cases of AKI patients treated to use respectively in which a non-RRT therapy of ABC.Therapy A is randomized treatment in 60 cases,32 cases in treatment group sequential treated by alprostadil (PGE1)with mannitol and furosemide,28 cases in control group treated with small dose of dopamine and furosemide; Therapy B by Shenkang injection(SKI) in 24 cases ;Therapy C by PGE1 and SKI combined with mannitol or furosemide sequential treatment in 13 cases.Results The total effective rate was 80％ (48/60)in therapy A,the cure rate and total effective rate of treatment group was better than control group(P ＜0.05) ;The total effective rate was 79.17％ (19/24) in therapy B;The total effective rate was 100％ (13/13)in therapy C.After the non-RRT in total 97 cases of AKI,80 cases (82.5 ％) cured or improved,17 cases (17.5 ％) need RRT,both comparative difference was statistically significant(P ＜ 0.01) Conclusions (1) Most of AKI can be successfully treated by medication,to need RRT only a small number.(2) Non-RRT has better curative effect on AKI by PGE1 combined with mannitol and furosemide on sequential treatment or SKI alone or these combined with sequential alliance.(3)The key to successful treatment is early diagnosis and early treatment.
