国际泌尿系统杂志
國際泌尿繫統雜誌
국제비뇨계통잡지
INTERNATIONAL JOURNAL OF UROLOGY AND NEPHROLOGY
2014年
3期
334-336
,共3页
肾肿瘤%脂肪瘤%肌,平滑,血管
腎腫瘤%脂肪瘤%肌,平滑,血管
신종류%지방류%기,평활,혈관
Kidney Neoplasms%Lipoma%Muscle,Smooth,Vascular
目的 探讨肾上皮样血管平滑肌脂肪瘤(AML)的临床特点及诊治经验.方法 回顾性分析4例肾上皮样AML的临床及病理特征.肾上皮样血管平滑肌脂肪瘤患者4例.肿瘤单发3例,多发1例.肿瘤直径4.5～ 12cm.CT检查发现肿瘤内含脂肪组织(CT值-80～ 30HU)2例,术前诊断为肾癌2例,肾血管平滑肌脂肪瘤2例.2例术前诊断为AML者采用保留肾单位手术,术前诊断为肾癌者2例行根治性肾切除.结果 病理检查报告:肿瘤有不完整假包膜3例,切面棕褐色或灰白色;1例肾根治性切除者肿瘤无包膜,呈浸润性生长,累及肾门血管周围脂肪组织,肿瘤中心有出血坏死灶;2例肿瘤内缺乏脂肪组织,可见多少不等的异常厚壁血管和平滑肌,上皮样肿瘤细胞围绕血管壁呈片状或腺泡状分布.免疫组化染色结果:黑色素细胞标记物(HMB45)和平滑肌标志物(SAM)阳性,上皮细胞标记(CK、EMA)阴性.结论 肾上皮样血管平滑肌脂肪瘤是较为罕见的具有恶性潜能的肿瘤,多为良性,部分缺乏脂肪组织,诊断中需要注意与肾细胞癌鉴别,手术为主要治疗方法.
目的 探討腎上皮樣血管平滑肌脂肪瘤(AML)的臨床特點及診治經驗.方法 迴顧性分析4例腎上皮樣AML的臨床及病理特徵.腎上皮樣血管平滑肌脂肪瘤患者4例.腫瘤單髮3例,多髮1例.腫瘤直徑4.5～ 12cm.CT檢查髮現腫瘤內含脂肪組織(CT值-80～ 30HU)2例,術前診斷為腎癌2例,腎血管平滑肌脂肪瘤2例.2例術前診斷為AML者採用保留腎單位手術,術前診斷為腎癌者2例行根治性腎切除.結果 病理檢查報告:腫瘤有不完整假包膜3例,切麵棕褐色或灰白色;1例腎根治性切除者腫瘤無包膜,呈浸潤性生長,纍及腎門血管週圍脂肪組織,腫瘤中心有齣血壞死竈;2例腫瘤內缺乏脂肪組織,可見多少不等的異常厚壁血管和平滑肌,上皮樣腫瘤細胞圍繞血管壁呈片狀或腺泡狀分佈.免疫組化染色結果:黑色素細胞標記物(HMB45)和平滑肌標誌物(SAM)暘性,上皮細胞標記(CK、EMA)陰性.結論 腎上皮樣血管平滑肌脂肪瘤是較為罕見的具有噁性潛能的腫瘤,多為良性,部分缺乏脂肪組織,診斷中需要註意與腎細胞癌鑒彆,手術為主要治療方法.
목적 탐토신상피양혈관평활기지방류(AML)적림상특점급진치경험.방법 회고성분석4례신상피양AML적림상급병리특정.신상피양혈관평활기지방류환자4례.종류단발3례,다발1례.종류직경4.5～ 12cm.CT검사발현종류내함지방조직(CT치-80～ 30HU)2례,술전진단위신암2례,신혈관평활기지방류2례.2례술전진단위AML자채용보류신단위수술,술전진단위신암자2례행근치성신절제.결과 병리검사보고:종류유불완정가포막3례,절면종갈색혹회백색;1례신근치성절제자종류무포막,정침윤성생장,루급신문혈관주위지방조직,종류중심유출혈배사조;2례종류내결핍지방조직,가견다소불등적이상후벽혈관화평활기,상피양종류세포위요혈관벽정편상혹선포상분포.면역조화염색결과:흑색소세포표기물(HMB45)화평활기표지물(SAM)양성,상피세포표기(CK、EMA)음성.결론 신상피양혈관평활기지방류시교위한견적구유악성잠능적종류,다위량성,부분결핍지방조직,진단중수요주의여신세포암감별,수술위주요치료방법.
Objectives To investigate the clinicopathologic features of epithelioid anglomyolipoma of the kidney.Methods Four cases of epithelioid anglomyolipoma of the kidney were analyzed by hisopathological and clinical characteristic.Of the 4 case,3 cases were solitary tumors and 1 cases were multiple lesions.The diameter of tumors was 4.5 ～ 12cm.Two cases were found adipose tissue in CT scan and diagnosed for epithelioid anglomyolipoma of renal,the other 2 cases were diagnosed for renal cancer.All cases were undergone surgical approach,2 cases were undergone resection of tumors only and the other 2 were performed nephrectomy.Results Pathological characters:epithelioid anglomyolipoma of the kidney was composed of abnormal thick parietal vessel,smooth muscle and adipose tissue in different proportional.The SMA and HMB45 were positive by immunohistochemisty.Conclusions Most of epithelioid anglomyolipoma of the kidney are benign and often misdiagnosed for renal cancer by CT scan.Operation is major method.
