CAJ | 학술논문

目的降低阴囊Paget's病的误诊率,提高早期诊断率及生存率.方法回顾性研究中山大学附属肿瘤医院(1999 ～2013年)36例阴囊Paget's病患者的临床资料,并进行随访及分析.结果 Ray分期A1期21例;A2期8例;B期6例;D期1例;其中阴囊Paget's病合并汗腺癌6例;早中期患者首选治疗方式为阴囊病灶广泛切除术;D期患者采用放疗.7例术后复发,其中1例行姑息性放疗及泰素+顺铂化疗;2例放疗;4例阴囊Paget's病复发灶切除术.36例患者随访平均时间40个月,3例死于肿瘤转移,生存时间分别为79个月,78个月,23个月;3例死于其他肿瘤,生存时间分别16个月,20个月,17个月.结论阴囊Paget's病患者早期活检是关键,手术彻底切除病灶是首选治疗方式,早期治疗预后良好.
목적 강저음낭Paget's병적오진솔,제고조기진단솔급생존솔.방법 회고성연구중산대학부속종류의원(1999 ～2013년)36례음낭Paget's병환자적림상자료,병진행수방급분석.결과 Ray분기A1기21례;A2기8례;B기6례;D기1례;기중음낭Paget's병합병한선암6례;조중기환자수선치료방식위음낭병조엄범절제술;D기환자채용방료.7례술후복발,기중1례행고식성방료급태소+순박화료;2례방료;4례음낭Paget's병복발조절제술.36례환자수방평균시간40개월,3례사우종류전이,생존시간분별위79개월,78개월,23개월;3례사우기타종류,생존시간분별16개월,20개월,17개월.결론 음낭Paget's병환자조기활검시관건,수술철저절제병조시수선치료방식,조기치료예후량호.
Objectives To reduce the scrotum paget's disease of the misdiagnosis rate,improve the early diagnostic rate and survival rate.Methods A retrospective study of tumor hospital affiliated to sun yat-sen university (1999-2013),the clinical data of 36 cases of paget's disease of the scrotum,and follow-up and analysis.Results Ray stage A1 21 cases;A2 8 cases;B 6 cases; D 1 case;The scrotum Paget's disease combined sweat gland carcinoma 6 cases;The preferred treatment for patients with early metaphase is scrotal lesion wide resection;D period were treated by radiotherapy.7 cases of postoperative recurrence,1 of whom underwent palliative radiotherapy and taxol + cisplatin chemotherapy ;2 cases of radiation ;4 cases of scrotal Paget's disease recurrence resection of oven.36 patients were followed for an average time of 40 months,3 cases died of tumor metastasis,and survival time of 79 month respectively,78 month,23 months;3 cases died of other tumors,survival time 16 months respectively,20months,17 months.Conclusions Scrotal Paget's disease early biopsy is the key,the operation complete resection of lesions is the preferred treatment,early treatment prognosis is good.