CAJ | 학술논문

目的结合病例报告及文献复习,探讨肾上腺恶性孤立性纤维性肿瘤(malignantsolitary fibrous tumor,MSFT)的临床特征、治疗方案及预后.方法对本院收治的1例肾上腺恶性孤立性纤维性肿瘤进行回顾性分析,并使用关键词”“孤立性纤维性肿瘤”检索“中国生物医学文献数据库”,同时使用Pubmed数据库检索“solitary fibrous tumor and adrenal”,对所得文献进行复习,对所有诊断为恶性孤立性纤维性肿瘤进行汇总分析.结果检索国内孤立性纤维性肿瘤文献共有241篇报道,其中病例报道130篇,恶性肿瘤有13篇,未见肾上腺MSFT个案报道.Pubmed结果提示目前共有5例孤立性纤维性肿瘤.结论肾上腺MSFT非常罕见,可发生在身体任何部位,确诊主要依靠病理形态学及免疫组化,治疗方案主要为手术切除,必要时可行术后放化疗,预后较差.
목적 결합병례보고급문헌복습,탐토신상선악성고립성섬유성종류(malignantsolitary fibrous tumor,MSFT)적림상특정、치료방안급예후.방법 대본원수치적1례신상선악성고립성섬유성종류진행회고성분석,병사용관건사”“고립성섬유성종류”검색“중국생물의학문헌수거고”,동시사용Pubmed수거고검색“solitary fibrous tumor and adrenal”,대소득문헌진행복습,대소유진단위악성고립성섬유성종류진행회총분석.결과 검색국내고립성섬유성종류문헌공유241편보도,기중병례보도130편,악성종류유13편,미견신상선MSFT개안보도.Pubmed결과제시목전공유5례고립성섬유성종류.결론 신상선MSFT비상한견,가발생재신체임하부위,학진주요의고병리형태학급면역조화,치료방안주요위수술절제,필요시가행술후방화료,예후교차.
Objectives Combined one case report and literatures review to explore the clinical characteristics,the management and prognosis of malignant solitary fibrous tumor(MSFT) of adrenal.Methods Retrospectively analyzed one case of MSFT of the adrenal which we treated.We used the key word" solitary fibrous tumor" to retrieve"the Chinese Biomedical Literature Database",and use the" solitary fibrous tumor"to retrieve" Pubmed" in internet.All the papers were readed and analysed,which is focusing on the the cases with MSFTs.Results There are 241 paper of solitary fibrous tumor collected in the" Chinese Biomedical Literature Database",including 130 cases report.There are 13 cases of MSFTs,and there is no case of MSFT of the adrenal.In the Pubmed,only 5 cases were reported in solitary fibrous tumor.Conclusions Malignant solitary fibrous tumor is very rare,occuring in any part of the body.The diagnosis were relied on pathological morphology and immunohistochemistry.The mainly treatment is the surgery,if necessary,radiotherapy and chemotherapy can be performed postoperative.However the prognosis is poor.