CAJ | 학술논문

低剂量电离辐射(LDR)诱导的兴奋性效应(hormesis)能增强受照机体的固有免疫和适应性免疫反应.以树突状细胞(DC)为基础的肿瘤免疫治疗开始于20世纪60年代,实验证实免疫治疗能在某种程度上提升抗肿瘤免疫应答和抑制肿瘤生长和转移.通过总结分析近几年的文献报道,可了解兴奋性效应增强免疫治疗临床效果的可能性.
저제량전리복사(LDR)유도적흥강성효응(hormesis)능증강수조궤체적고유면역화괄응성면역반응.이수돌상세포(DC)위기출적종류면역치료개시우20세기60년대,실험증실면역치료능재모충정도상제승항종류면역응답화억제종류생장화전이.통과총결분석근궤년적문헌보도,가료해흥강성효응증강면역치료림상효과적가능성.
Low dose radiation (LDR)-induced hormesis could largely strengthen innate immune response and adaptive immune response . Dendritic cells (DC)-based immunotherapy begun in the 1960's,Currently,abundant related literatures have been proved that immunotherapy could enhance antitumor immune response and inhibit tumor growth,metastasis to some extent. This review summarized recent reports and outlooked the possibility that whether hormesis could enhance the clinical effects of immunotherapy