国际免疫学杂志
國際免疫學雜誌
국제면역학잡지
INTERNATIONAL JOURNAL OF IMMUNOLOGY
2013年
5期
341-346
,共6页
髓样细胞表达的激发型受体%炎症反应%配体
髓樣細胞錶達的激髮型受體%炎癥反應%配體
수양세포표체적격발형수체%염증반응%배체
Triggering receptors expressed by myeloid cells%Inflammatory%Ligand
髓样细胞表达的激发型受体(TREM)是新近发现的免疫球蛋白超家族的一个受体家族,它主要包括TREM-1、TREM-2、TLT-1和TLT-2四个家族成员.自2000年发现TREM-1以来,TREM家族就成为了人们关注的对象,特别是近年来针对TREM-1与炎症反应的关系及TLT-2配体的研究更是成为了研究的热点.因此对TREM家族全面的认识,有助于其家族信号通路和生物学功能的进一步研究.
髓樣細胞錶達的激髮型受體(TREM)是新近髮現的免疫毬蛋白超傢族的一箇受體傢族,它主要包括TREM-1、TREM-2、TLT-1和TLT-2四箇傢族成員.自2000年髮現TREM-1以來,TREM傢族就成為瞭人們關註的對象,特彆是近年來針對TREM-1與炎癥反應的關繫及TLT-2配體的研究更是成為瞭研究的熱點.因此對TREM傢族全麵的認識,有助于其傢族信號通路和生物學功能的進一步研究.
수양세포표체적격발형수체(TREM)시신근발현적면역구단백초가족적일개수체가족,타주요포괄TREM-1、TREM-2、TLT-1화TLT-2사개가족성원.자2000년발현TREM-1이래,TREM가족취성위료인문관주적대상,특별시근년래침대TREM-1여염증반응적관계급TLT-2배체적연구경시성위료연구적열점.인차대TREM가족전면적인식,유조우기가족신호통로화생물학공능적진일보연구.
Triggering receptor expressed by myeloid cells (TREM) is a newly discovered immunoglobulin superfamily.It mainly includes TREM-1,TREM-2,TLT-1 and TLT-2.Trem-1 was discovered by Buchon in 2000,then the family draw attention,especially in recent years.The relationship between TREM-1,inflammatory and the ligand of TLT-2 become research hotspots.Therefore,the research on the TREM family may contribute to know more.Intormation about signaling pathways and biological function of this family.
