CAJ | 학술논문

CD10分子最初作为普通急性淋巴细胞白血病抗原(CALLA)被发现,是一个相对分子质量为90 000-110 000Ⅱ型单链穿膜糖蛋白.CD10分子广泛分布在各种组织,具有中性肽链内切酶(NEP)的功能,并且表达在不同的组织,其功能不尽相同.目前广泛应用于用血液系统肿瘤以及部分实体肿瘤的诊断和预后判断,还用于造血细胞分化发育研究和部分组织干细胞的研究.
CD10분자최초작위보통급성림파세포백혈병항원(CALLA)피발현,시일개상대분자질량위90 000-110 000Ⅱ형단련천막당단백.CD10분자엄범분포재각충조직,구유중성태련내절매(NEP)적공능,병차표체재불동적조직,기공능불진상동.목전엄범응용우용혈액계통종류이급부분실체종류적진단화예후판단,환용우조혈세포분화발육연구화부분조직간세포적연구.
Human CD10 molecul,which was found as the common acute lymphoblastic leukemia anti-gen (CALLA),is a type Ⅱ single-chain transmembrane glycoprotein (90 000-110 000),expressed broadly on varied tissues.CD10 is a neutral endopeptidase (NEP),and it performs different function in different organs.Anti CD10 antibodies are used for the detection and prognosis of leukemia and solid tumor,as well as for research in hematopoietic and tissue stem cells.