CAJ | 학술논문

随着研究的不断深入,人们对维生素D的认识不再局限于钙、磷以及骨代谢.在各种免疫细胞中均存在维生素D受体及代谢相关的酶.维生素D与免疫的关系愈来愈受到重视.维生素D在免疫细胞的作用机制也逐步明确.越来越多的临床随机对照试验显示,维生素D有利于免疫功能,尤其在自身免疫性疾病、抗感染等方面发挥着重要作用.目前,维生素D介导下的免疫耐受作用机制探究正在成为新的研究热点.
수착연구적불단심입,인문대유생소D적인식불재국한우개、린이급골대사.재각충면역세포중균존재유생소D수체급대사상관적매.유생소D여면역적관계유래유수도중시.유생소D재면역세포적작용궤제야축보명학.월래월다적림상수궤대조시험현시,유생소D유리우면역공능,우기재자신면역성질병、항감염등방면발휘착중요작용.목전,유생소D개도하적면역내수작용궤제탐구정재성위신적연구열점.
The correlation between vitamin D and immunity attracts more attention.Nowadays,It has been recognized that vitamin D receptor and its metabolic enzymes exist in various immunocyte and its functions were not confined to the metabolism of calcium and phosphorus.Randomized clinical trials suggest that vitamin D plays an important role in immune function,particularly in autoimmune diseases and infectious diseases.Recently,the mechanism of immune tolerance mediated by vitamin D has been a hot topic of research.