CAJ | 학술논문

固有免疫作为机体的第一道防线,在免疫系统中发挥着极其重要的作用,近年来,异常的固有免疫反应在慢性阻塞性肺疾病(COPD)的发病以及进展中的作用受到越来越多的关注.吸烟是COPD的主要危险因素,香烟烟雾会导致气道持续不断地炎症反应,是COPD病情不断进展和病理变化不可逆的主要原因.进一步研究吸烟对固有免疫的影响可以更加深刻了解COPD的发病机制,为COPD的预防和治疗提供理论基础.
고유면역작위궤체적제일도방선,재면역계통중발휘착겁기중요적작용,근년래,이상적고유면역반응재만성조새성폐질병(COPD)적발병이급진전중적작용수도월래월다적관주.흡연시COPD적주요위험인소,향연연무회도치기도지속불단지염증반응,시COPD병정불단진전화병리변화불가역적주요원인.진일보연구흡연대고유면역적영향가이경가심각료해COPD적발병궤제,위COPD적예방화치료제공이론기출.
As the first line of defense,innate immunity plays an important role in the immune system.In recent years,the effect of abnormal innate immunity reaction on the development of chronic obstructive pulmonary disease (COPD) is attracting more and more attention.Smoking is the main risk factors of COPD.Cigarette smoke can lead to continuous airway inflammation and irreversible pathological changes in the lung.Smoking is the main causes of the development of COPD.To further study the effects of smoking on the innate immunity can Contribute to understanding the pathogenesis prevention,and treatment of COPD.