CAJ | 학술논문

目的探讨高血压患者围术期压力反射敏感性(baroreflex sensitivity,BRS)的变化规律及自主神经功能状态.方法采用有创动脉测压测定48例高血压患者(包括24例经治疗的患者及24例未经治疗的患者)及48例非高血压患者在给予硝酸甘油前后的血压、心率变化,根据Robert公式计算出BRS值. 结果高血压患者术前BRS值(3.3±2.0)、术中的BRS值(1.7±1.1)明显低于非高血压患者[术前、术中分别是(5.7±4.1)和(3.3±3.1)](P＜0.01),未经治疗的高血压患者术前BRS值(2.1±1.3)、术中BRS值(1.5±0.9)、术毕时的BRS值(1.4±1.3)明显低于经治疗的高血压患者[术前、术中、术毕分别是(5.3±1.8)、(2.0±1.8)、(1.8±1.2)](P＜0.01). 结论高血压患者围术期的自主神经功能明显受损,经治疗的高血压患者围术期的自主神经功能有所改善.
목적 탐토고혈압환자위술기압력반사민감성(baroreflex sensitivity,BRS)적변화규률급자주신경공능상태.방법 채용유창동맥측압측정48례고혈압환자(포괄24례경치료적환자급24례미경치료적환자)급48례비고혈압환자재급여초산감유전후적혈압、심솔변화,근거Robert공식계산출BRS치. 결과 고혈압환자술전BRS치(3.3±2.0)、술중적BRS치(1.7±1.1)명현저우비고혈압환자[술전、술중분별시(5.7±4.1)화(3.3±3.1)](P＜0.01),미경치료적고혈압환자술전BRS치(2.1±1.3)、술중BRS치(1.5±0.9)、술필시적BRS치(1.4±1.3)명현저우경치료적고혈압환자[술전、술중、술필분별시(5.3±1.8)、(2.0±1.8)、(1.8±1.2)](P＜0.01). 결론 고혈압환자위술기적자주신경공능명현수손,경치료적고혈압환자위술기적자주신경공능유소개선.
Objective To analyze perioperative baroreflex sensitivity (BRS) in patients with hypertention and the autonomic nerve activity.Methods Blood pressure and heart rate before and after injection nitroglycerin were measured in patients with hypertension or without (n=48 including 24 undergoing treatment patients).BRS was calculated according to Robert formula.Results BRS Baseline(3.3±2.0) and BRS intraoperative(1.7±1.1) in patients with hypertension were obviously lower than those in non-hypertension patients [(5.7±4.1),(3.3±3.1) respectively,P＜0.01].BRS Baseline (2.1±1.3),BRS intraoperative (1.5±0.9)and BRS postoperative (1.4±1.3) in patients without treatment were lower than those in patients undergoing treatment [(5.3±1.8),(2.0±1.8),(1.8±1.2) respectively,P＜0.01].Conclusions The perioperative autonomic nerve function is significantly impaired in patients with hypertension.And the impaired autonomic can be improved by treatment.