CAJ | 학술논문

背景急性肾损伤(acute kidney injury,AKI)是外科重症患者术后常见并发症之一,其发病率和死亡率均较高,严重地威胁了患者的生命安全. 目的为了早期有效识别和诊断外科重症患者术后发生的AKI并及时地提供诊治措施以降低AKI的发病率、改善这类患者的结局.现就这类新型标记物的研究进展作一综述. 内容主要针对外科重症患者,探讨新型标记物检测在其灵敏性和特异性以及AKI病情评估方面相对于传统检测的优势. 趋向未来对于外科重症具有高AKI风险因素的患者采用新型标记物外科联合检测将有利于术后AKI的早期诊断和预后评估.
배경 급성신손상(acute kidney injury,AKI)시외과중증환자술후상견병발증지일,기발병솔화사망솔균교고,엄중지위협료환자적생명안전. 목적 위료조기유효식별화진단외과중증환자술후발생적AKI병급시지제공진치조시이강저AKI적발병솔、개선저류환자적결국.현취저류신형표기물적연구진전작일종술. 내용 주요침대외과중증환자,탐토신형표기물검측재기령민성화특이성이급AKI병정평고방면상대우전통검측적우세. 추향 미래대우외과중증구유고AKI풍험인소적환자채용신형표기물외과연합검측장유리우술후AKI적조기진단화예후평고.
Background As one of common postoperative complications in critically ill surgical patients,the incidence and mortality of acute renal injury were higher,and which seriously threaten the safety of surgery patients.Objective This article reviews the research progress of the novel markers,in order to timely identify and diagnose acute kidney injury (AKI),reduce the incidence of postoperative AKI,improve the outcomes of surgical critically ill patients with AKI.Content To evaluate the sensitivity and specificity of novel markers for AKI,and compare its superiority of diagnosis for AKI with the traditional detection in surgical critically ill patients Trend Using combined detection with novel markers will be good for early diagnosis and prognosis evaluation of postoperative AKI in critically ill patients with high risk factors of AKI in the future.