国际内分泌代谢杂志
國際內分泌代謝雜誌
국제내분비대사잡지
INTERNATIONAL JOURNAL OF ENDOCRINOLOGY AND METABOLISM
2013年
1期
36-39
,共4页
胰岛素抵抗%高血压%胰岛素
胰島素牴抗%高血壓%胰島素
이도소저항%고혈압%이도소
Insulin resistance%Hypertension%Insulin
研究表明胰岛素抵抗与高血压密切相关,胰岛素抵抗是高血压的一个独立危险因子,二者存在理论上的因果关系.胰岛素抵抗在高血压的发病机制中起至关重要的作用,而高血压也可影响胰岛素的代谢,造成胰岛素抵抗,两者相辅相成,导致一系列严重慢性并发症的发生.同时,多种降压药物可通过影响糖代谢从而改善胰岛素抵抗,另一方面,部分改善胰岛素抵抗的药物可用于治疗原发性高血压.因此,了解胰岛素抵抗与高血 压之间的关系对于胰岛素抵抗及高血压的防治有重要意义.
研究錶明胰島素牴抗與高血壓密切相關,胰島素牴抗是高血壓的一箇獨立危險因子,二者存在理論上的因果關繫.胰島素牴抗在高血壓的髮病機製中起至關重要的作用,而高血壓也可影響胰島素的代謝,造成胰島素牴抗,兩者相輔相成,導緻一繫列嚴重慢性併髮癥的髮生.同時,多種降壓藥物可通過影響糖代謝從而改善胰島素牴抗,另一方麵,部分改善胰島素牴抗的藥物可用于治療原髮性高血壓.因此,瞭解胰島素牴抗與高血 壓之間的關繫對于胰島素牴抗及高血壓的防治有重要意義.
연구표명이도소저항여고혈압밀절상관,이도소저항시고혈압적일개독립위험인자,이자존재이론상적인과관계.이도소저항재고혈압적발병궤제중기지관중요적작용,이고혈압야가영향이도소적대사,조성이도소저항,량자상보상성,도치일계렬엄중만성병발증적발생.동시,다충강압약물가통과영향당대사종이개선이도소저항,령일방면,부분개선이도소저항적약물가용우치료원발성고혈압.인차,료해이도소저항여고혈 압지간적관계대우이도소저항급고혈압적방치유중요의의.
Studies have shown that hypertension is closely related with insulin resistance.Insulin re-sistance is an independent risk factor of hypertension,and there is causal relationship between them.Insulin resistance plays a vital role in the pathogenesis of hypertension,and hypertension also affects the metabolism of insulin.They complement each other,and then result in a series of serious chronic complications.Multiple antihypertensive drugs can improve insulin resistance through affecting glucose metabolism.On the other hand,some drugs which can improve insulin resistance can be used to treat primary hypertension.Therefore,understanding the relationship between insulin resistance and hypertension has an important significance in prevention and treatment of insulin resistance and hypertension.