CAJ | 학술논문

目的探讨缺血性卒中后非流利性失语患者静息态功能磁共振成像(functionalmagnetic resonance imaging fMRI)的脑功能特点.方法对17例缺血性卒中后非流利性失语患者以及19名年龄、性别和受教育程度均匹配的健康对照者进行静息态fMRI检查,采用局部区域一致性(regional homogeneity,ReHo)分析方法计算静息态下脑区的ReHo情况.结果与对照组比较,患者组左侧额上回、右侧额下回、右侧脑岛以及右侧缘上回ReHo值增高,右侧小脑半球、左侧颞上回、颞中回以及右侧颞下回脑区ReHo值降低.结论在静息状态下,缺血性卒中后非流利性失语患者存在多个脑区ReHo异常,这种异常改变可能与其功能损伤后修复的代偿作用有关.
목적 탐토결혈성졸중후비류리성실어환자정식태공능자공진성상(functionalmagnetic resonance imaging fMRI)적뇌공능특점.방법 대17례결혈성졸중후비류리성실어환자이급19명년령、성별화수교육정도균필배적건강대조자진행정식태fMRI검사,채용국부구역일치성(regional homogeneity,ReHo)분석방법계산정식태하뇌구적ReHo정황.결과 여대조조비교,환자조좌측액상회、우측액하회、우측뇌도이급우측연상회ReHo치증고,우측소뇌반구、좌측섭상회、섭중회이급우측섭하회뇌구ReHo치강저.결론 재정식상태하,결혈성졸중후비류리성실어환자존재다개뇌구ReHo이상,저충이상개변가능여기공능손상후수복적대상작용유관.
Objective To investigate the brain function characteristics of resting-state functional magnetic resonance imaging (fMRI) in patients with non-fluent aphasia after ischemic stroke.Methods Seventeen patients with non-fluent aphasia after ischemic stroke and 19 age-,sex-,and education-matched normal healthy subjects were examined with resting-state fMRI.The regional homogeneity (ReHo) analysis was used to calculate the ReHo of resting state in brain regions.Results Compared to the control group,the ReHo values of left superior frontal gyrus,right inferior frontal gyrus,right insular,and supramarginal gyrus increased in the aphasia group; the ReHo values of right cerebellar hemisphere,left superior temporal gyrus,left middle temporal gyrus,and right inferior temporal gyrus decreased.Conelusions In the resting state,the patients with non-fluent aphasia have ReHo anomalies in multiple brain regions.Such abnormal changes may be associated with the compensatory role of repairing after functional damage.