CAJ | 학술논문

目的探讨Vogt-Koyanagi综合征的临床特点,尤其是皮肤和毛发的表现.方法回顾性分析1998 - 2008年的22例Vogt-Koyanagi综合征患者的临床资料.结果 22例患者中男8例,女14例,男女比例1:1.75,平均年龄为47.86岁.20例(90.9%)的患者出现前驱症状,头痛是最常见的症状.17例(77.3%)患者出现皮肤和毛发的改变,包括白发、脱发、斑秃和皮肤白斑,2例患者出现肢端白斑(Sigiura征).13例(59.1%)患者出现神经系统和耳部的表现.所有患者均出现前葡萄膜炎,2例患者出现日落征,2例患者出现Dalen-Fuchs结节.结论皮肤和毛发改变是Vogt-Koyanagi综合征的重要眼外表现之一.
목적 탐토Vogt-Koyanagi종합정적림상특점,우기시피부화모발적표현.방법 회고성분석1998 - 2008년적22례Vogt-Koyanagi종합정환자적림상자료.결과 22례환자중남8례,녀14례,남녀비례1:1.75,평균년령위47.86세.20례(90.9%)적환자출현전구증상,두통시최상견적증상.17례(77.3%)환자출현피부화모발적개변,포괄백발、탈발、반독화피부백반,2례환자출현지단백반(Sigiura정).13례(59.1%)환자출현신경계통화이부적표현.소유환자균출현전포도막염,2례환자출현일락정,2례환자출현Dalen-Fuchs결절.결론 피부화모발개변시Vogt-Koyanagi종합정적중요안외표현지일.
Objective To investigaie the clinical manifestations of, especially skin and hair changes in Vogt-Koyanagi-Harada syndrome (VKHs). Methods Clinical data were retrospectively assessed on 22 patients with VKHs collected at Beijing Hospital from 1998 to 2008. Results There were 8 males and 14 females. With the ratio of male to female 1 : 1.75 and mean age 47.86 years. Both eyes were involved in all of the patients. Twenty (90. 9%) patients presented with prodrome, and headache was the most common syndrome.of the patients, 17 (77.3) showed changes of skin and hair, including leukotrichia,alopecia, alopecia areata and vitiligo, 2 Sigiura's sign, 13 (59.1%) neurological and auditory syndrome, 2 typical sunset glow fundus, 2 Dalen-Fuchs nodules. Conclusion Skin and hair changes are important extraocular manifestations of VKHs.