CAJ | 학술논문

患者女,9岁.左侧躯体皮肤红色斑丘疹、斑块伴左下肢畸形9年就诊.体检:患者跛行左下肢较右侧明显短小,左足2、3、4趾畸形.左侧肢体肌张力下降,肌力较对侧弱.皮肤科检查:左侧后颈部、臀部、会阴部、小腿、足部明显红色肥厚性斑块.皮损组织病理检查:表皮角化过度,真皮乳头少量泡沫细胞浸润,真皮浅层灶性淋巴细胞和浆细胞浸润.免疫组化检查:真皮乳头泡沫细胞CD68、CD163强阳性,但不表达S100.诊断为CHILD综合征.
환자녀,9세.좌측구체피부홍색반구진、반괴반좌하지기형9년취진.체검:환자파행좌하지교우측명현단소,좌족2、3、4지기형.좌측지체기장력하강,기력교대측약.피부과검사:좌측후경부、둔부、회음부、소퇴、족부명현홍색비후성반괴.피손조직병리검사:표피각화과도,진피유두소량포말세포침윤,진피천층조성림파세포화장세포침윤.면역조화검사:진피유두포말세포CD68、CD163강양성,단불표체S100.진단위CHILD종합정.
A 9-year-old girl was born with cutaneous erythema and plaques on the left side of the body as well as deformity of the left lower limb.Physical examination revealed limp,obvious shortening of the left lower limb,deformity of the second,third and fourth toes of the left foot.Both muscle tone and muscle strength were decreased in the left lower limb compared with the right lower limb.Cutaneous examination showed erythematous hypertrophic plaques in the left posterior neck,buttock,perineum,leg,and foot.Histopathologic examination of the skin lesions showed epidermal hyperkeratosis,a small number of foamy cells infiltrating the dermal papillae,as well as focal lymphocyte and plasma cell infiltrates in the superficial dermis.Moreover,the foamy cells in the dermal papillae stained strongly positive for CD68 and CD163,but negative for S100.A diagnosis of CHILD syndrome was made.