国际皮肤性病学杂志
國際皮膚性病學雜誌
국제피부성병학잡지
INTERNATIONAL JOURNAL OF DERMATOLOGY AND VENEREOLOGY
2013年
6期
354-358
,共5页
肖学敏%张晓峰%李诚让%王宝玺
肖學敏%張曉峰%李誠讓%王寶璽
초학민%장효봉%리성양%왕보새
痤疮,寻常%综合征%研究
痤瘡,尋常%綜閤徵%研究
좌창,심상%종합정%연구
Acne,vulgaris%Syndrome%Research
近年来研究表明,痤疮不仅是一种皮肤病,也是一些系统疾病或综合征的主要表现,在某些情况下可能反映存在系统异常,并为研究性激素、先天性/获得性免疫、炎症反应及遗传因素的相互作用提供了一个理想的疾病模型.了解这些综合征的分子机制、临床表现及治疗进展有助于深入理解痤疮的发病机制,开发出治疗痤疮的新方法.
近年來研究錶明,痤瘡不僅是一種皮膚病,也是一些繫統疾病或綜閤徵的主要錶現,在某些情況下可能反映存在繫統異常,併為研究性激素、先天性/穫得性免疫、炎癥反應及遺傳因素的相互作用提供瞭一箇理想的疾病模型.瞭解這些綜閤徵的分子機製、臨床錶現及治療進展有助于深入理解痤瘡的髮病機製,開髮齣治療痤瘡的新方法.
근년래연구표명,좌창불부시일충피부병,야시일사계통질병혹종합정적주요표현,재모사정황하가능반영존재계통이상,병위연구성격소、선천성/획득성면역、염증반응급유전인소적상호작용제공료일개이상적질병모형.료해저사종합정적분자궤제、림상표현급치료진전유조우심입리해좌창적발병궤제,개발출치료좌창적신방법.
Recent studies have shown that acne is not only a kind of dermatosis but also a main presentation of many systemic diseases and syndromes.In some cases,acne reflects the presence of systemic abnormalities,and can serve as an ideal model for investigations into the interactions among hormones,innate/ acquired immunity,inflammatory response and genetic factors.To learn the progress in molecular mechanisms,clinical manifestations and treatment of acne-associated syndromes will be beneficial to the understanding of acne pathogenesis and development of new therapies for acne.