CAJ | 학술논문

酒渣鼻是一种常见的面部慢性炎症性皮肤病,其发病机制尚不明确,其中微生物起重要作用.蠕形螨虫与酒渣鼻发病有密切相关,可能通过Ⅳ型免疫反应致病.在对蠕形螨虫所携带的细菌的研究中,人们发现奥列伦芽胞杆菌、表皮葡萄球菌可能由蠕形螨虫携带,并与之共同致病;幽门螺杆菌、小肠细菌过度生长等可能在合并消化道症状的酒渣鼻发病中起作用,但其相关性和致病机制并不确切.目前尚未发现痤疮丙酸杆菌、沃尔巴克体与酒渣鼻发病有关.
주사비시일충상견적면부만성염증성피부병,기발병궤제상불명학,기중미생물기중요작용.연형만충여주사비발병유밀절상관,가능통과Ⅳ형면역반응치병.재대연형만충소휴대적세균적연구중,인문발현오렬륜아포간균、표피포도구균가능유연형만충휴대,병여지공동치병;유문라간균、소장세균과도생장등가능재합병소화도증상적주사비발병중기작용,단기상관성화치병궤제병불학절.목전상미발현좌창병산간균、옥이파극체여주사비발병유관.
Rosacea is a common chronic inflammatory skin disease that predominantly affects the central regions of the face.Its pathogenesis remains unknown,and microorganisms are considered to play an important role in its development.Demodex mites contribute a lot to the development of rosacea,probably through type Ⅳ immunological reaction.Bacillus olemnius and Staphylococcus epidermidis,which are found to be carried by Demodex mites,may synergistically collaborate with Demodex mites in the pathogenesis of rosacea.Besides,Helicobacter pylod and small intestinal bacterial overgrowth may be involved in the initiation of rosacea complicated by digestive tract symptoms,but the correlation and mechanisms remain unclear.There has been no evidence for the correlation between rosacea and Propionibactedum acnes or Wolbachia.