国际生物医学工程杂志
國際生物醫學工程雜誌
국제생물의학공정잡지
INTERNATIONAL JOURNAL OF BIOMEDICAL ENGINEERING
2012年
6期
332-336,342
,共6页
孙健%熊耀阳%陈萍%张富强
孫健%熊耀暘%陳萍%張富彊
손건%웅요양%진평%장부강
三维打印成型%多孔钛植入体%组织结构%力学性能
三維打印成型%多孔鈦植入體%組織結構%力學性能
삼유타인성형%다공태식입체%조직결구%역학성능
Three dimensional printing%Porous titanium implants%Structure%Mechanical properties
目的 评价三维打印成型技术(3DP)用于多孔钛植入体制备的可行性,研究不同烧结温度对其组织结构和力学性能的影响.方法 设计试件大小为25×20 mm圆柱体,设定每层的黏结面积为80％.选择纯度98.5％、颗粒直径约75 μm的钛粉为原料,聚乙烯醇粉作为黏结剂,聚乙烯吡咯烷酮粉作为辅助黏结剂.通过三维打印获得多孔钛植入体试件初胚,在氩气保护下,将试件分别烧结至1 200、1 300、1 400℃；对烧结完成的试件进行性能检测,包括孔隙率、显微硬度、扫描电镜观察试件的显微结构、抗压强度及弹性模量.结果 最终获得的多孔钛植入体试件,其收缩均匀、无明显变形、细节清晰、肉眼可见排列整齐的微孔结构、表面无裂纹,呈现金属光泽.在1 200、1 300、1 400℃的烧结温度下,孔隙率分别为(65.01±1.03)％、(46.73±0.73)％、(41.06±0.31)％,显微硬度为115.2±0.6、148.6±1.1、182.8±2.1,弹性模量为(5.9±0.5)、(16.2±0.9)、(34.8±1.5) GPa,抗压强度为(81.3±4.3)、(135.4±8.5)、(218.6±7.1)MPa.扫描电镜观察其孔隙相互连通成三维网状结构.结论 证实了应用三维打印成型技术制备多孔钛植入体的可行性,得到的多孔钛植入体具有与骨组织相匹配的良好的生物力学相容性.
目的 評價三維打印成型技術(3DP)用于多孔鈦植入體製備的可行性,研究不同燒結溫度對其組織結構和力學性能的影響.方法 設計試件大小為25×20 mm圓柱體,設定每層的黏結麵積為80％.選擇純度98.5％、顆粒直徑約75 μm的鈦粉為原料,聚乙烯醇粉作為黏結劑,聚乙烯吡咯烷酮粉作為輔助黏結劑.通過三維打印穫得多孔鈦植入體試件初胚,在氬氣保護下,將試件分彆燒結至1 200、1 300、1 400℃；對燒結完成的試件進行性能檢測,包括孔隙率、顯微硬度、掃描電鏡觀察試件的顯微結構、抗壓彊度及彈性模量.結果 最終穫得的多孔鈦植入體試件,其收縮均勻、無明顯變形、細節清晰、肉眼可見排列整齊的微孔結構、錶麵無裂紋,呈現金屬光澤.在1 200、1 300、1 400℃的燒結溫度下,孔隙率分彆為(65.01±1.03)％、(46.73±0.73)％、(41.06±0.31)％,顯微硬度為115.2±0.6、148.6±1.1、182.8±2.1,彈性模量為(5.9±0.5)、(16.2±0.9)、(34.8±1.5) GPa,抗壓彊度為(81.3±4.3)、(135.4±8.5)、(218.6±7.1)MPa.掃描電鏡觀察其孔隙相互連通成三維網狀結構.結論 證實瞭應用三維打印成型技術製備多孔鈦植入體的可行性,得到的多孔鈦植入體具有與骨組織相匹配的良好的生物力學相容性.
목적 평개삼유타인성형기술(3DP)용우다공태식입체제비적가행성,연구불동소결온도대기조직결구화역학성능적영향.방법 설계시건대소위25×20 mm원주체,설정매층적점결면적위80％.선택순도98.5％、과립직경약75 μm적태분위원료,취을희순분작위점결제,취을희필각완동분작위보조점결제.통과삼유타인획득다공태식입체시건초배,재아기보호하,장시건분별소결지1 200、1 300、1 400℃；대소결완성적시건진행성능검측,포괄공극솔、현미경도、소묘전경관찰시건적현미결구、항압강도급탄성모량.결과 최종획득적다공태식입체시건,기수축균균、무명현변형、세절청석、육안가견배렬정제적미공결구、표면무렬문,정현금속광택.재1 200、1 300、1 400℃적소결온도하,공극솔분별위(65.01±1.03)％、(46.73±0.73)％、(41.06±0.31)％,현미경도위115.2±0.6、148.6±1.1、182.8±2.1,탄성모량위(5.9±0.5)、(16.2±0.9)、(34.8±1.5) GPa,항압강도위(81.3±4.3)、(135.4±8.5)、(218.6±7.1)MPa.소묘전경관찰기공극상호련통성삼유망상결구.결론 증실료응용삼유타인성형기술제비다공태식입체적가행성,득도적다공태식입체구유여골조직상필배적량호적생물역학상용성.
Objective The aim of this study was to evaluate the feasibility of three-dimensional printing (3DP) for the preparation of porous titanium implant and to investigate the impacts on microstructure and mechanical properties with different sintering temperatures.Methods The CAD model of the specimens was designed to be 25 mm in diameter,20 mm in height,and with 0.5 mm pore size mesh.On every cross-section,80％ bonding area was designed.Titanium powder (purity of 98.5％,75 μm diameter) was selected as raw material.Polyvinyl alcohol powder (160 μm diameter) was selected as a binder,and polyvinylpyrrolidone powder was selected as an auxiliary binder.The green porous titanium implants were fabricated by 3DP followed by sintering at 1 200,1 300,1 400 ℃,separately,under the protection of argon gas.After sintering,the properties of porous titanium implants were evaluated,including the porosity,microstructure,microhardness,compressive strength and elastic modulus.Results After sintering,the specimen had uniform contraction and no obvious distortion.The specimen sintered at 1 200,1 300 and 1 400 ℃ sintering temperatures had porosity of (65.01±1.03)％,(46.73±0.73)％ and (41.06±0.31)％,hardness of 115.2±0.6,148.6±1.1 and 182.8±2.1,elastic modulus of (5.9±0.5),(16.2±0.9) and (34.8±1.5) GPa,compressive strength of (81.3±4.3),(135.4±8.5) and (218.6±7.1) MPa,respectively.A porous structure with three-dimensional network of connected pores was observed under scanning electron microscope.Conclusion It is feasible to fabricate porous titanium implants by three dimensional printing technique.The mechanical properties of the porous titanium implants match well with bone tissue which has excellent biomechanical compatibility.
