CAJ | 학술논문

一种新颖的近红外(NIR)光扩散相关谱(DCS)技术最近被研发出来用于无创检测光动力治疗(PDT)期间的肿瘤血流量变化.DCS为肿瘤血流量测量提供了一些有吸引力的新特征如无创性、可携带性、低成本、高的时间分辨率和相对较大的穿透深度.DCS技术已被用于连续监测PDT引起的人体及动物肿瘤血流量的变化.这些研究的最终目标是利用监测PDT对肿瘤血流动力学的影响来预测和优化治疗效果.
일충신영적근홍외(NIR)광확산상관보(DCS)기술최근피연발출래용우무창검측광동력치료(PDT)기간적종류혈류량변화.DCS위종류혈류량측량제공료일사유흡인력적신특정여무창성、가휴대성、저성본、고적시간분변솔화상대교대적천투심도.DCS기술이피용우련속감측PDT인기적인체급동물종류혈류량적변화.저사연구적최종목표시이용감측PDT대종류혈류동역학적영향래예측화우화치료효과.
A novel near-infrared (NIR) diffuse correlation spectroscopy (DCS) has recently been developed for noninvasive monitoring of tumor blood flow during photodynamic therapy (PDT).DCS offers several attractive new features for tumor blood flow measurement such as noninvasiveness,portability,low cost,high temporal resolution and relatively large penetration depth.DCS technology has been utilized for continuous measurement of tumor blood flow before,during and after PDT in both animals and humans.The ultimate goal is to predict treatment outcomes from the measured tumor hemodynamic responses to PDT.