国际生物医学工程杂志
國際生物醫學工程雜誌
국제생물의학공정잡지
INTERNATIONAL JOURNAL OF BIOMEDICAL ENGINEERING
2013年
5期
277-281
,共5页
彩色多普勒超声%主动脉瓣钙化%相关危险因素
綵色多普勒超聲%主動脈瓣鈣化%相關危險因素
채색다보륵초성%주동맥판개화%상관위험인소
Color Doppler echocardiograph%Aortic valve calcification%Correlative risk factors
目的 探讨彩色多普勒超声心动图对老年退行性主动脉瓣钙化的诊断价值并分析其相关危险因素.方法 应用彩色多普勒超声心动图检查110例患主动脉瓣钙化(AVC)患者(研究组)和110例主动脉瓣无钙化者(对照组)的主动脉瓣,伴有主动脉和主动脉瓣钙化的患者均除外先天性和其他后天性瓣膜疾患.观察主动脉瓣的形态,测量主动脉根部的径线,同时探测主动脉收缩期和舒张期的血流峰值并比较2组不同特征以及研究AVC与某些相关危险因素的关系.结果 研究组显示因钙化而造成主动脉瓣环前后径及瓣口面积缩小;主动脉窦部前后径扩大和跨瓣压力阶差升高;大动脉及外周动脉粥样硬化(AS)及动脉狭窄检出率高于对照组;AS会使脉压差增大,并加重AVC;相关危险因素除年龄外还有高血压病、高脂血症、骨质疏松等疾病.以上结果与对照组相比,均具有统计学意义(P＜0.05).这些相关疾病的诊断均以临床检验结果为准,伴随相关危险因素越多,AVC发生越明显;此外,性别和升主动脉径线2组比较,其差别无统计学意义(P＞0.05).相关因素中糖尿病与AVC发生率2组比较,其差别无统计学意义(P＞0.05).结论 老年退行性主动脉瓣钙化可造成老年人主动脉瓣及大血管形态异常改变和功能障碍.伴有相关危险因素的老年人,相关因素越多,主动脉瓣及大血管形态异常改变及功能障碍越明显.
目的 探討綵色多普勒超聲心動圖對老年退行性主動脈瓣鈣化的診斷價值併分析其相關危險因素.方法 應用綵色多普勒超聲心動圖檢查110例患主動脈瓣鈣化(AVC)患者(研究組)和110例主動脈瓣無鈣化者(對照組)的主動脈瓣,伴有主動脈和主動脈瓣鈣化的患者均除外先天性和其他後天性瓣膜疾患.觀察主動脈瓣的形態,測量主動脈根部的徑線,同時探測主動脈收縮期和舒張期的血流峰值併比較2組不同特徵以及研究AVC與某些相關危險因素的關繫.結果 研究組顯示因鈣化而造成主動脈瓣環前後徑及瓣口麵積縮小;主動脈竇部前後徑擴大和跨瓣壓力階差升高;大動脈及外週動脈粥樣硬化(AS)及動脈狹窄檢齣率高于對照組;AS會使脈壓差增大,併加重AVC;相關危險因素除年齡外還有高血壓病、高脂血癥、骨質疏鬆等疾病.以上結果與對照組相比,均具有統計學意義(P＜0.05).這些相關疾病的診斷均以臨床檢驗結果為準,伴隨相關危險因素越多,AVC髮生越明顯;此外,性彆和升主動脈徑線2組比較,其差彆無統計學意義(P＞0.05).相關因素中糖尿病與AVC髮生率2組比較,其差彆無統計學意義(P＞0.05).結論 老年退行性主動脈瓣鈣化可造成老年人主動脈瓣及大血管形態異常改變和功能障礙.伴有相關危險因素的老年人,相關因素越多,主動脈瓣及大血管形態異常改變及功能障礙越明顯.
목적 탐토채색다보륵초성심동도대노년퇴행성주동맥판개화적진단개치병분석기상관위험인소.방법 응용채색다보륵초성심동도검사110례환주동맥판개화(AVC)환자(연구조)화110례주동맥판무개화자(대조조)적주동맥판,반유주동맥화주동맥판개화적환자균제외선천성화기타후천성판막질환.관찰주동맥판적형태,측량주동맥근부적경선,동시탐측주동맥수축기화서장기적혈류봉치병비교2조불동특정이급연구AVC여모사상관위험인소적관계.결과 연구조현시인개화이조성주동맥판배전후경급판구면적축소;주동맥두부전후경확대화과판압력계차승고;대동맥급외주동맥죽양경화(AS)급동맥협착검출솔고우대조조;AS회사맥압차증대,병가중AVC;상관위험인소제년령외환유고혈압병、고지혈증、골질소송등질병.이상결과여대조조상비,균구유통계학의의(P＜0.05).저사상관질병적진단균이림상검험결과위준,반수상관위험인소월다,AVC발생월명현;차외,성별화승주동맥경선2조비교,기차별무통계학의의(P＞0.05).상관인소중당뇨병여AVC발생솔2조비교,기차별무통계학의의(P＞0.05).결론 노년퇴행성주동맥판개화가조성노년인주동맥판급대혈관형태이상개변화공능장애.반유상관위험인소적노년인,상관인소월다,주동맥판급대혈관형태이상개변급공능장애월명현.
Objective To investigate the value of the senile degenerative aortic valve calcification (AVC) and to analyze the correlative risk factors by color Doppler echocardiograph.Methods Aortic valves of 110 cases with AVC (study group) and 110 cases without AVC (control group) were observed by color Doppler echocardiograph.All the patients with AVC have been excluded of congenital and other acquired valves' diseases.The aortic valve' s shape and the diameters of aortic root were measured.At the same time,the peak systolic and diastolic velocities of aorta were detected.The different features were compared between the two groups.Results Test results showed significant differences in study group:Anteroposterior diameter of aortic annulus and the area of aortic valve were decreased by calcification; The anteroposterior diameter of aortic sinus increased and aorta transvalvular pressure gradient augmented; Detection rate of atherosclerosis (AS) of aorta and the peripheral artery stenosis of the study group were higher than that of control group; The AS increased pulse pressure and aggravated AVC; Correlative risk factors,in addition to age,included hypertension,hypercholesterolemia,osteoporosis,and so on.The correct diagnosis of the correlated diseases were on the basis of clinical examines.The rate of AVC with multi-factor was higher than that with single-factor.In addition,gender difference and the diameters of ascending aortic showed no significant difference in two groups.Relationship between diabetes of correlative factors and the rate of AVC showed no significant difference in two groups.Conclusion Morphologic abnormality and malfunction of aortic valve and the large artery in elder patients were caused by senile degenerative AVC.The more correlative risk factors,the worse showed.
