CAJ | 학술논문

大量输血方案(MTP)是指以标准流程的形式指导大出血和创伤性凝血病的治疗,涉及浓缩红细胞、新鲜冰冻血浆、血小板等的输注及重组凝血因子的使用时间、剂量和时间等方面.该过程需要急诊科、外科、检验科、血库等多部门的积极协作.MTP可优化血液制品的输注流程,避免在危急和快速运作情况下发生错误,可减少血液制品的使用总量,提高输血效率,减轻创伤性凝血病的严重程度,改善严重创伤患者的生存率,减少输血相关并发症.现就MTP及其研究进展综述如下.
대량수혈방안(MTP)시지이표준류정적형식지도대출혈화창상성응혈병적치료,섭급농축홍세포、신선빙동혈장、혈소판등적수주급중조응혈인자적사용시간、제량화시간등방면.해과정수요급진과、외과、검험과、혈고등다부문적적겁협작.MTP가우화혈액제품적수주류정,피면재위급화쾌속운작정황하발생착오,가감소혈액제품적사용총량,제고수혈효솔,감경창상성응혈병적엄중정도,개선엄중창상환자적생존솔,감소수혈상관병발증.현취MTP급기연구진전종술여하.
Massive transfusion protocols (MTP) are well established principles to guide the treatment of massive bleeding and traumatic coagulopathy,which involve the timing,dose and aim of utilization of packed red blood cell (PRBC),fresh frozen plasma (FFP),platelet (PLT) and recombinant factors.These processes require collaboration among different departments,such as emergency department,trauma surgery,laboratory department and blood bank.MTP plays an important role on reducing the amount of blood products used,improving transfusion efficiency,reducing the severity of traumatic coagulopathy,increasing the survival rate of patients and decreasing the transfusion-related complications.Now,MTP and its' research progress are summarized below.