CAJ | 학술논문

肝脏手术中为控制出血常需要阻断肝脏血管,造成肝脏缺血再灌注损伤,而肝脏缺血再灌注损伤是影响肝脏术后肝脏功能恢复的一个重要因素,是由许多因子参与的复杂的病理生理过程.随着人们对缺血再灌注损伤机制研究的深入,有效地防治缺血再灌注损伤的措施也取得了进展,肝脏手术预后得到改善.本文就肝脏缺血再灌注损伤机制及防治措施的进展进行综述.
간장수술중위공제출혈상수요조단간장혈관,조성간장결혈재관주손상,이간장결혈재관주손상시영향간장술후간장공능회복적일개중요인소,시유허다인자삼여적복잡적병리생리과정.수착인문대결혈재관주손상궤제연구적심입,유효지방치결혈재관주손상적조시야취득료진전,간장수술예후득도개선.본문취간장결혈재관주손상궤제급방치조시적진전진행종술.
Ischemia reperfusion injury is an important factor which has been affected the recuperation of hepatic function after hepatectomy and liver transplantation,and is a complex course in pathophysiology with many factors.With the development of research on ischemia reperfusion injury,effective prevention measures of ischemia reperfusion injury also have made new progress.And this will greatly improve the prognosis of hepatic surgery.The mechanism and its prevention measure of hepatic ischemia reperfusion injury were reviewed in this paper.