CAJ | 학술논문

目的汇总分析国内蓝色橡皮疱痣综合征的文献,探讨中国患者蓝色橡皮疱痣综合征临床特点和诊治策略.方法在中国期刊全文数据库、万方数据库及维普中文科技期刊数据库中检索,提取符合要求的文献进行总结分析.结果 50例患者纳入研究,其中男性31例,女性19例.100％出现皮肤血管瘤,其他主要临床症状:黑便35例(70％),便血13例(26％),头晕心悸35例(70％).胃镜检查48例,发现胃血管瘤40例(40/48,83.33％);结肠镜检查41例,发现结肠血管瘤30例(30/41,73.17％);小肠检查25例,发现小肠血管瘤23例(23/25,92％).单纯药物支持治疗14例;单纯内镜治疗12例患者,所有单纯内镜下治疗病变均局限于胃及结肠;单纯手术治疗16例;2例为腹腔镜联合内镜下治疗.结论蓝色橡皮疱痣综合征是罕见的疾病.在中国患者中,皮肤和消化道是常累及的部位.对小肠部位的检查应作为常规检查.有效的治疗方法尚需要进一步研究.
목적 회총분석국내람색상피포지종합정적문헌,탐토중국환자람색상피포지종합정림상특점화진치책략.방법 재중국기간전문수거고、만방수거고급유보중문과기기간수거고중검색,제취부합요구적문헌진행총결분석.결과 50례환자납입연구,기중남성31례,녀성19례.100％출현피부혈관류,기타주요림상증상:흑편35례(70％),편혈13례(26％),두훈심계35례(70％).위경검사48례,발현위혈관류40례(40/48,83.33％);결장경검사41례,발현결장혈관류30례(30/41,73.17％);소장검사25례,발현소장혈관류23례(23/25,92％).단순약물지지치료14례;단순내경치료12례환자,소유단순내경하치료병변균국한우위급결장;단순수술치료16례;2례위복강경연합내경하치료.결론 람색상피포지종합정시한견적질병.재중국환자중,피부화소화도시상루급적부위.대소장부위적검사응작위상규검사.유효적치료방법상수요진일보연구.
Objective The study was performed to analyze the diagnosis and treatment of blue rubber bleb nevus syndrome of Chinese patients by evaluating the researches in China.Methods Chinese Journal Full-text Database,Wangfang Data and Weipu Chinese Medical Journal Database were searched for the clinical data of the patients with blue rubber bled nevus syndrome.Results Among the 50 patients,31 cases were male,and 19 cases were female.All patients (100％) had the venous malformations of the skin.Thirty-five (70％) cases had melena,13 (26％) cases had bloody stool,and 35(70％) had dizziness and palpitation.Blue rubber bled nevus syndrome were diagnosed with gastroscopy (40/48,83.33 ％),coloscopy (30/41,73.17％) and small intestinal examination (23/25,92％).Fourteen cases received symptomatic treatment.Twelve cases received therapeutic endoscopy,which lesions were located in stomach and colon.Sixteen cases received operation,and 2 cases were treated by laparoscopy and endoscopy.Conclusions Blue rubber bleb nevus syndrome is a rare disease.The skin and gastrointestinal system are involved in all patients with blue rubber bleb nevus syndrome in China.The routine examination for diagnosis of blue rubber bleb nevus syndrome should include examination of the small intestine.It still needs further research about effective treatment of blue rubber bleb nevus syndrome.