CAJ | 학술논문

随着肝脏外科技术的发展,围手术期管理和患者筛选标准的进步使可以接受半肝切除术或扩大肝切除术的患者数量大大增加.而肝切除术后肝功能衰竭是肝切除术后严重的并发症之一,肝切除术后肝功能衰竭患者相关风险中糖尿病及已有肝脏疾病如肝硬化、脂肪肝、胆汁淤积等是最重要的危险因素.手术相关风险中残肝体积及术中大出血是影响肝切除术后肝功能衰竭发病率及病死率的关键因素.而到目前为止还没有很好的方法治疗肝功能衰竭,所以预防显得尤为重要.
수착간장외과기술적발전,위수술기관리화환자사선표준적진보사가이접수반간절제술혹확대간절제술적환자수량대대증가.이간절제술후간공능쇠갈시간절제술후엄중적병발증지일,간절제술후간공능쇠갈환자상관풍험중당뇨병급이유간장질병여간경화、지방간、담즙어적등시최중요적위험인소.수술상관풍험중잔간체적급술중대출혈시영향간절제술후간공능쇠갈발병솔급병사솔적관건인소.이도목전위지환몰유흔호적방법치료간공능쇠갈,소이예방현득우위중요.
Advances in hepatic surgical technique,perioperative care and improvements in patient selection criteria have increased the number of patients who could undergo major or extended hepatectomy with curative intent.Posthepatectomy liver failure (PHLF) is one of the most serious complications after liver resection.Different risk factors are related to the occurrence of PHLF,among surgery-related factors,massive bleeding and remnant liver volume were related to higher frequency of PHLF.The presence of diabetes and liver disease such as cirrhosis,cholestasis,steatosis had been involved with the occurrence of PHLF.So far there is no good method for the treatment of PHLF,so prevention is very important.