CAJ | 학술논문

根据心房颤动(简称房颤)的遗传性和家族聚集性,可分为家族性房颤和非家族性房颤.房颤的发生机制尚未明确,但研究显示基因突变是其致病因素之一.近年来通过对家族性房颤进行基因遗传性研究,已经发现部分离子通道和非离子通道致病基因,现就以上领域的研究进展予以综述.
근거심방전동(간칭방전)적유전성화가족취집성,가분위가족성방전화비가족성방전.방전적발생궤제상미명학,단연구현시기인돌변시기치병인소지일.근년래통과대가족성방전진행기인유전성연구,이경발현부분리자통도화비리자통도치병기인,현취이상영역적연구진전여이종술.
According to genetic predisposition and familial aggregation,atrial fibrillation (AF) is divided into familial atrial fibrillation and non-familial atrial fibrillation.The mechanism of atrial fibrillation has not been yet clear,but researches showed that gene mutation was one of the pathogenic factors.In recent years,some pathogenic genes including encoding part of the ion channels and non-ion channels found to corralate with the onset of familial AF will be reviewed here.