CAJ | 학술논문

甲状腺相关眼病(thyroid associated ophthalmopathy,TAO)是一种自身免疫性疾病,临床表现为眼球突出、眼睑退缩、复视、角膜及视神经损伤等.各国学者采用一般生存质量量表、视功能损害相关性量表和甲状腺相关眼病生存质量量表评估TAO患者的生存质量及各种干预方式对其生存质量的影响,发现TAO引起的外观改变及视功能损害影响了患者的工作和生活,患者的精神心理压力巨大,生存质量严重下降.激素冲击、放射疗法、眶减压术等各种干预方式能一定程度改善患者生存质量,但效果不甚满意.开发适合TAO生存质量的评估体系及研究改善生存质量的手段是目前的研究热点和重点.
갑상선상관안병(thyroid associated ophthalmopathy,TAO)시일충자신면역성질병,림상표현위안구돌출、안검퇴축、복시、각막급시신경손상등.각국학자채용일반생존질량량표、시공능손해상관성량표화갑상선상관안병생존질량량표평고TAO환자적생존질량급각충간예방식대기생존질량적영향,발현TAO인기적외관개변급시공능손해영향료환자적공작화생활,환자적정신심리압력거대,생존질량엄중하강.격소충격、방사요법、광감압술등각충간예방식능일정정도개선환자생존질량,단효과불심만의.개발괄합TAO생존질량적평고체계급연구개선생존질량적수단시목전적연구열점화중점.
Thyroid associated ophthalmopathy(TAO)is an autoimmune disease causing proptosis,eyelid retraction,motility disorders with diplopia,corneal damage,compressed optic nerve and so on.Researchers found that physical discomfort,facial disfigurement and impaired visual function caused by TAO have a negative impact on patients'employment,daily life,psychosocial function and their quality of life(QOL),using general health-related QOL questionnaires,vision-specific questionnaires and disease-specific QOL questionnaires.Intervening measures,including surgery,intravenous methylprednisolone,orbital radiotherapy and so on,could improve patients’QOL,but not satisfying.In this review,we assess the evidence of the impact on patients'QOL,improving means and the social care of TAO.