CAJ | 학술논문

目的总结分析首都医科大学附属北京朝阳医院泌尿外科肾移植患者术后并发恶性肿瘤的临床特点,探讨其诊治方法.方法回顾性分析1998至2012年肾移植患者中发生恶性肿瘤的病例.结果在2893例肾移植者中,96例发生恶性肿瘤,发病率为3.32％.其中泌尿系统肿瘤76例(包括移植肾肾癌1例),胃癌5例,直肠癌4例,肝细胞癌3例,宫颈癌3例,前列腺癌2例,肺癌2例,胰腺癌1例.结论肾移植术后恶性肿瘤发病率明显升高,其中泌尿系统肿瘤居多;由慢性间质性肾炎导致肾功能衰竭的肾移植患者术后尿路上皮肿瘤好发;对移植后出现肿瘤类型的不同可采用不同的治疗方法;早期诊治是提高患者生存率的关键.
목적 총결분석수도의과대학부속북경조양의원비뇨외과신이식환자술후병발악성종류적림상특점,탐토기진치방법.방법 회고성분석1998지2012년신이식환자중발생악성종류적병례.결과 재2893례신이식자중,96례발생악성종류,발병솔위3.32％.기중비뇨계통종류76례(포괄이식신신암1례),위암5례,직장암4례,간세포암3례,궁경암3례,전렬선암2례,폐암2례,이선암1례.결론 신이식술후악성종류발병솔명현승고,기중비뇨계통종류거다;유만성간질성신염도치신공능쇠갈적신이식환자술후뇨로상피종류호발;대이식후출현종류류형적불동가채용불동적치료방법;조기진치시제고환자생존솔적관건.
Objective To analyze clinical features of post-transplantation malignant tumor in renal allograft recipients.Methods A retrospective study was conducted in renal allograft recipients in Chaoyang Hospital between 1998 and 2003.Results Of 2893 renal allograft recipients,96 (3.32％) were diagnosed with malignant tumors,76 of which were urinary system carcinoma,9 were gastric and rectal carcinoma,3 were hepatocellular carcinoma,3 were cervical cancer,2 were prostate cancer,2 were lung cancer and one was pancreas cancer.Conclusion The incidence of malignant tumor in renal transplant recipients,especially the urinary system carcinoma,is significantly increased; urothelial carcinoma is a common complication in renal allograft recipients with chronic interstitial nephritis; the type of malignant tumor is associated with treatment.