CAJ | 학술논문

细胞凋亡是为维持机体内环境稳态而由基因控制的细胞自主性死亡,是细胞生长发育过程中的重要机制.近年来研究发现,细胞凋亡可通过直接接触或释放一系列调控因子直接或间接地影响微环境中邻近细胞的生理过程,在构建肿瘤微环境中有重要作用.了解细胞凋亡在正常和肿瘤组织微环境中的作用对深入研究肿瘤的发生机制、预防及治疗具有重要意义.
세포조망시위유지궤체내배경은태이유기인공제적세포자주성사망,시세포생장발육과정중적중요궤제.근년래연구발현,세포조망가통과직접접촉혹석방일계렬조공인자직접혹간접지영향미배경중린근세포적생리과정,재구건종류미배경중유중요작용.료해세포조망재정상화종류조직미배경중적작용대심입연구종류적발생궤제、예방급치료구유중요의의.
Apoptosis is the autonomous death of cells,which is controlled by the genes and to maintain the homeostasis of the body.Apoptosis is the important mechanism in the cell's growth and development.Recent studies have found that apoptosis can affect the neighboring cells physiological process in microenvironment through directly contact or release a series of regulatory factor,which plays an important roles in the construction of tumor microenvironment.Therefore,understanding the roles of apoptosis in the normal and tumor microenvironment has great significance for further study the pathogenesis,prevention and treatment of tumor.