国际肿瘤学杂志
國際腫瘤學雜誌
국제종류학잡지
JOURNAL OF INTERNATIONAL ONCOLOGY
2013年
2期
153-156
,共4页
蒋蓓琦%傅韵%武弈%成小林%李正东%庄志刚
蔣蓓琦%傅韻%武弈%成小林%李正東%莊誌剛
장배기%부운%무혁%성소림%리정동%장지강
乳腺肿瘤%癌,导管内,非浸润性%生活质量%36条目简明量表
乳腺腫瘤%癌,導管內,非浸潤性%生活質量%36條目簡明量錶
유선종류%암,도관내,비침윤성%생활질량%36조목간명량표
Breast neoplasms%Carcinoma%intraductal,noninfiltrating%Quality of life%SF-36
目的 调查乳腺导管原位癌(DCIS)患者生活质量(QOL),分析其相关影响因素.方法 采用36条目简明量表(SF-36),对术后1年的84例DCIS患者、125例浸润性乳腺癌患者进行QOL评估,分析年龄、手术方式、内分泌治疗、学历、婚姻状况、工作状态、医疗保险对患者QOL的影响.结果 与正常女性相比,术后1年的DCIS患者在生理功能(t=2.468,P=0.029)、躯体疼痛(=2.076,P=0.039)、总体健康(t=2.153,P=0.033)和精神健康(=3.396,P=0.003)4个维度得分较低,而浸润性乳腺癌患者在生理功能(t=5.638,P=0.002)、躯体疼痛(t=5.417,P=0.002)、活力(t=4.438,P=0.002)、总体健康(=3.960,P=0.002)和精神健康(t=6.020,P=0.001)5个维度得分低于正常.两组患者QOL大致相似,有6个维度得分差异无统计学意义,但在生理功能(t=2.714,P=0.032)和活力(t =2.134,P=0.040)方面DCIS患者优于浸润性癌患者.术后内分泌治疗是影响DCIS患者QOL的重要因素,显著降低了患者生理功能(t=2.082)、躯体疼痛(t=2.003)、总体健康(=2.751)、活力(t=2.048)和精神健康(t=4.162)5个维度得分,P均小于0.05.结论 术后1年DCIS患者QOL较差,内分泌治疗是重要影响因素.
目的 調查乳腺導管原位癌(DCIS)患者生活質量(QOL),分析其相關影響因素.方法 採用36條目簡明量錶(SF-36),對術後1年的84例DCIS患者、125例浸潤性乳腺癌患者進行QOL評估,分析年齡、手術方式、內分泌治療、學歷、婚姻狀況、工作狀態、醫療保險對患者QOL的影響.結果 與正常女性相比,術後1年的DCIS患者在生理功能(t=2.468,P=0.029)、軀體疼痛(=2.076,P=0.039)、總體健康(t=2.153,P=0.033)和精神健康(=3.396,P=0.003)4箇維度得分較低,而浸潤性乳腺癌患者在生理功能(t=5.638,P=0.002)、軀體疼痛(t=5.417,P=0.002)、活力(t=4.438,P=0.002)、總體健康(=3.960,P=0.002)和精神健康(t=6.020,P=0.001)5箇維度得分低于正常.兩組患者QOL大緻相似,有6箇維度得分差異無統計學意義,但在生理功能(t=2.714,P=0.032)和活力(t =2.134,P=0.040)方麵DCIS患者優于浸潤性癌患者.術後內分泌治療是影響DCIS患者QOL的重要因素,顯著降低瞭患者生理功能(t=2.082)、軀體疼痛(t=2.003)、總體健康(=2.751)、活力(t=2.048)和精神健康(t=4.162)5箇維度得分,P均小于0.05.結論 術後1年DCIS患者QOL較差,內分泌治療是重要影響因素.
목적 조사유선도관원위암(DCIS)환자생활질량(QOL),분석기상관영향인소.방법 채용36조목간명량표(SF-36),대술후1년적84례DCIS환자、125례침윤성유선암환자진행QOL평고,분석년령、수술방식、내분비치료、학력、혼인상황、공작상태、의료보험대환자QOL적영향.결과 여정상녀성상비,술후1년적DCIS환자재생리공능(t=2.468,P=0.029)、구체동통(=2.076,P=0.039)、총체건강(t=2.153,P=0.033)화정신건강(=3.396,P=0.003)4개유도득분교저,이침윤성유선암환자재생리공능(t=5.638,P=0.002)、구체동통(t=5.417,P=0.002)、활력(t=4.438,P=0.002)、총체건강(=3.960,P=0.002)화정신건강(t=6.020,P=0.001)5개유도득분저우정상.량조환자QOL대치상사,유6개유도득분차이무통계학의의,단재생리공능(t=2.714,P=0.032)화활력(t =2.134,P=0.040)방면DCIS환자우우침윤성암환자.술후내분비치료시영향DCIS환자QOL적중요인소,현저강저료환자생리공능(t=2.082)、구체동통(t=2.003)、총체건강(=2.751)、활력(t=2.048)화정신건강(t=4.162)5개유도득분,P균소우0.05.결론 술후1년DCIS환자QOL교차,내분비치료시중요영향인소.
Objective To study the quality of life (QOL) of patients with ductal carcinoma in situ (DCIS) and to analyze the relevant factors affecting their QOL.Methods A total of 84 patients with DCIS and 125 patients with invasive breast cancer were surveyed.Researchers used SF-36 to assess the QOL of participants at one year after operation.The relationships between some information of patients and SF-36 score were analyzed,such as age,the type of surgery,endocrine therapy,education,marital status,working status and health insurance.Results Compared to normal women,patients with DCIS had lower QOL in physical function (t =2.468,P =0.029),bodily pain (t =2.076,P =0.039),general health (t =2.153,P =0.033) and mental health (t =3.396,P =0.003).Patients with invasive breast cancer also had poorer QOL in physical function (t =5.638,P =0.002),bodily pain (t =5.417,P =0.002),vitality (t =4.438,P =0.002),general health (t =3.960,P =0.002) and mental health (t =6.020,P =0.001).QOL of DCIS patients was similar to that of invasive breast cancer patients,except that scores of physical function (t =2.714,P =0.032) and vitality (t =2.134,P =0.040) were better in DCIS patients.Endocrine therapy significantly affected the score of QOL of DCIS patients.DCIS patients with endocrine therapy had poorer score in physical function (t =2.082,P ＜ 0.05),bodily pain (t =2.003,P ＜ 0.05),general health (t =2.751,P ＜0.05),vitality (t =2.048,P ＜ 0.05) and mental health (t =4.162,P ＜ 0.05).Conclusion Patients with DCIS have poor QOL at one year after operation.Endocrine therapy significantly reduces their QOL.
