CAJ | 학술논문

胶质母细胞瘤(GBM)术后放疗大都采用MRI与CT融合影像来勾画靶区,但是否包含瘤周水肿区尚有争议.根据术后、放疗后的复发范围,不论靶区设计是否包含水肿区,大部分复发都发生在磁共振(MRI)显示增强原发肿瘤灶外2 cm之内,瘤周水肿程度与复发模式无必然关系.GBM的临床和病理特征对放化疗疗效预测和预后也有重要指导意义.GBM的靶区设计趋向于个体化,可在保证疗效的同时减少治疗毒性.
효질모세포류(GBM)술후방료대도채용MRI여CT융합영상래구화파구,단시부포함류주수종구상유쟁의.근거술후、방료후적복발범위,불론파구설계시부포함수종구,대부분복발도발생재자공진(MRI)현시증강원발종류조외2 cm지내,류주수종정도여복발모식무필연관계.GBM적림상화병리특정대방화료료효예측화예후야유중요지도의의.GBM적파구설계추향우개체화,가재보증료효적동시감소치료독성.
The use of adjuvant extemal-beam RT is well established in the postoperative treatment of glioblastoma multiforme (CBM).It is consensus that target volume should be determined based on the fusion images of MRI and CT,but the inclusion of peritumoural edematous is controversial.The vast majority of recurrences occur within 2 cm of the original tumor site or " in radiation field".There is no inevitable relation between the degree of peritumoral edema and recurrence model.The clinical and pathological characteristics may be as predictive and prognostic factors for the treatment of GBM.Target volume delineation for CBM tend to individual,which can maintain known outcomes and reduce treatment toxicity.